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Displaying results 3751 - 3760 of 10000 in total
  1. Target

    Orotidine 5'-phosphate decarboxylase

    go.drugbank.com/bio_entities/BE0001956
    TargetBacillus subtilis (strain 168)

    Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

    Polypeptides: Orotidine 5'-phosphate decarboxylaseFunction: orotidine-5'-phosphate decarboxylase activity
  2. Target

    Inosine-5'-monophosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0002047
    TargetStreptococcus pyogenes

    Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays

    Polypeptides: Inosine-5'-monophosphate dehydrogenase
  3. Target

    Laminin subunit alpha-5

    go.drugbank.com/bio_entities/BE0002103
    TargetHumans

    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Plays a...

    Polypeptides: Laminin subunit alpha-5Synonyms: Laminin-10 subunit alpha
  4. Target

    Somatostatin receptor type 5

    go.drugbank.com/bio_entities/BE0002147
    TargetHumans

    Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization

    Polypeptides: Somatostatin receptor type 5Synonyms: SS-5-R
  5. Target

    Pyrroline-5-carboxylate reductase

    go.drugbank.com/bio_entities/BE0002335
    TargetHumans

    Polypeptides: Pyrroline-5-carboxylate reductaseFunction: pyrroline-5-carboxylate reductase activity
  6. Target

    Deoxyuridine 5'-triphosphate nucleotidohydrolase

    go.drugbank.com/bio_entities/BE0003348
    TargetPlasmodium falciparum (isolate 3D7)

    Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

    Polypeptides: Deoxyuridine 5'-triphosphate nucleotidohydrolaseSynonyms: Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative
  7. Target

    Nuclear receptor coactivator 5

    go.drugbank.com/bio_entities/BE0004057
    TargetHumans

    Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the or...

    Polypeptides: Nuclear receptor coactivator 5Synonyms: NCoA-5
  8. Target

    Interferon-inducible GTPase 5

    go.drugbank.com/bio_entities/BE0004634
    TargetHumans

    GTPase required for sperm motility and therefore male fertility, via positive regulation of spermatozoa fibrous sheath formation

    Polypeptides: Interferon-inducible GTPase 5
  9. Target

    Pyridoxine 5'-phosphate phosphatase

    go.drugbank.com/bio_entities/BE0004713
    EnzymeEnsifer meliloti

    Polypeptides: Pyridoxine 5'-phosphate phosphatase
  10. Target

    Inosine-5'-monophosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0004941
    TargetHumans

    Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays … Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays

    Polypeptides: Inosine-5'-monophosphate dehydrogenase 1, Inosine-5'-monophosphate dehydrogenase 2Synonyms: Inosine-5'-monophosphate dehydrogenase type II