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Displaying results 3751 - 3760 of 10000 in total
  1. Drug

    Fruquintinib

    go.drugbank.com/drugs/DB11679
    ApprovedInvestigational

    The first approach can be exemplified by [bevacizumab], a VEGF-A trap antibody. … This approval is based on favorable results obtained from the FRESCO and FRESCO-2 trials, where an increase in overall survival rate was observed in both trials.[L48791]

    Categories: Antineoplastic and Immunomodulating Agents
  2. Drug

    Papain

    go.drugbank.com/drugs/DB11193
    ApprovedWithdrawn

    Papain is also used as an ingredient in various enzymatic debriding preparations. … The enzyme is found to be localized in the skin of papaya, and is collected from slashed unripe papayas as a crude latex. Papain is used in food, pharmaceutical, textile, and cosmetic industries.

    Mixtures: Bromelain and Papain Tab, NATURE'S BOUNTY NATUREL B-COMPLEX AND B-12 TABLET, 90 ADETCategories: Enzymes and Coenzymes
  3. Drug

    Poloxamer 188

    go.drugbank.com/drugs/DB11333
    Approved

    P188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the blood before transfusions, however it is no longer available in any approved products [A27217]. … There is an evidence of P188 increasing the structural stability and resealing of the plasma membrane via direct incorporation into the phospholipid bilayer [A27217].

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Spirapril

    go.drugbank.com/drugs/DB01348
    ApprovedInvestigational

    ACE inhibitors are used primarily in treatment of hypertension and congestive heart failure. … Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration.

    Categories: Amino Acids, Peptides, and Proteins, Agents Acting on the Renin-Angiotensin System
  5. Indication

    T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

    go.drugbank.com/conditions/DBCOND0082251
    Drugs: Polatuzumab vedotin
    Synonyms: Malignant lymphoma, large cell, cleaved and noncleaved, Malignant lymphoma - large cell cleaved and non-cleaved
  6. Drug

    Pork collagen

    go.drugbank.com/drugs/DB14100
    Approved

    The surgical implantation shows a tolerable safety profile and efficacy up to 4 years, but it is not indicated for patients with osteoarthritis. … It has been used since 1995 as Carticel and gained biologic license in 1997. The surgical implantation was first performed in Sweden.

  7. Drug

    Aluminium phosphate

    go.drugbank.com/drugs/DB14517
    ApprovedInvestigational

    Categories: Alimentary Tract and Metabolism, Aluminum and magnesium containing antacids
  8. Drug

    Triprolidine

    go.drugbank.com/drugs/DB00427
    Approved

    First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.

    Mixtures: COUGH-EN LINCTUS, COUGH-EN LINCTUS
  9. Drug

    Metipranolol

    go.drugbank.com/drugs/DB01214
    ApprovedWithdrawn

    A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.

    Categories: Beta Blocking Agents and Thiazides, Antiglaucoma Preparations and Miotics
  10. Drug

    Beremagene geperpavec

    go.drugbank.com/drugs/DB17831
    ApprovedInvestigational

    [L46916] DEB is caused by mutations in the _COL7A1_ gene that encodes collagen VII (COL7), a major component of the anchoring fibrils for dermal–epidermal cohesion. … Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB).

    Categories: Cellular and Gene Therapy, Preparations for Treatment of Wounds and Ulcers