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Navafenterol
go.drugbank.com/drugs/DB19195InvestigationalNavafenterol is under investigation in clinical trial NCT02971293 (Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871).
Gastric intrinsic factor
go.drugbank.com/drugs/DB09349ApprovedIntrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach that is necessary for the absorption of vitamin B12 (cobalamin) later … However, it is currently in the marketed (but unapproved) product Hematogen in combination with cyanocobalamin (synthetic Vitamin B12), ferrous fumarate, and ascorbic acid for the treatment of anemias
Ospemifene
go.drugbank.com/drugs/DB04938ApprovedOspemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause
Categories: Selective Estrogen Receptor Modulators, Cytochrome P-450 SubstratesSynonyms: 2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanolTiagabine
go.drugbank.com/drugs/DB00906ApprovedTiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBetrixaban
go.drugbank.com/drugs/DB12364Approvedfor VTE [A27285]. … VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients [A27287].
Categories: P-glycoprotein substratesClocortolone
go.drugbank.com/drugs/DB00838ApprovedClocortolone is a medium potency corticosteroid that is often used as a topical cream for the relief of inflammatory oand pruritic (itching) arising from steroid-responsive dermatoses of the scalp.
Categories: Corticosteroid Hormone Receptor AgonistsATB-346
go.drugbank.com/drugs/DB15377InvestigationalATB-346 is under investigation in clinical trial NCT03220633 (Study To Assess Safety, Tolerability And PK Of ATB-346 In Healthy Subjects).
Difelikefalin
go.drugbank.com/drugs/DB11938ApprovedInvestigational[L36420,L36395] Difelikefalin was later approved by the EMA in April 2022 for the same indication.[L41665] … Difelikefalin (CR845) is an agonist of kappa opioid receptors (KORs) useful in the treatment of pruritus secondary to chronic kidney disease. KORs were first associated with itching in 1984.
Categories: Kappa Opioid Receptor Agonist