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Gastric intrinsic factor
go.drugbank.com/drugs/DB09349ApprovedIntrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach that is necessary for the absorption of vitamin B12 (cobalamin) later … However, it is currently in the marketed (but unapproved) product Hematogen in combination with cyanocobalamin (synthetic Vitamin B12), ferrous fumarate, and ascorbic acid for the treatment of anemias
Technetium Tc-99m succimer
go.drugbank.com/drugs/DB09436Approved[L40558] The use of technetium Tc-99m succimer for the detection of kidney cortical defects was first approved by the FDA on February 23, 2022, under the market name NephroScan.[L40573]
Levamlodipine
go.drugbank.com/drugs/DB09237ApprovedInvestigational[L1484] The names S-amlodipine and levamlodipine may be used interchangeably as both substances are the same, however. … Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of [amlodipine], an antihypertensive medication.
Categories: Antihypertensive Agents Indicated for Hypertension, P-glycoprotein substratesDesogestrel
go.drugbank.com/drugs/DB00304ApprovedInvestigational[A176339] It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological activity.
Categories: Hormonal Contraceptives for Systemic Use, Cytochrome P-450 SubstratesCetrelimab
go.drugbank.com/drugs/DB15421InvestigationalCetrelimab is under investigation in clinical trial NCT03547037 (A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of JNJ-63723283, an Anti-Programmed Cell Death (PD
Nitrazepam
go.drugbank.com/drugs/DB01595ApprovedA benzodiazepine derivative used as an anticonvulsant and hypnotic.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 InhibitorsClocortolone
go.drugbank.com/drugs/DB00838ApprovedClocortolone is a medium potency corticosteroid that is often used as a topical cream for the relief of inflammatory oand pruritic (itching) arising from steroid-responsive dermatoses of the scalp.
Categories: Corticosteroid Hormone Receptor AgonistsCretostimogene grenadenorepvec
go.drugbank.com/drugs/DB05148InvestigationalCG0070, an oncolytic virus therapy with specificity for multiple cancers, has been evaluated in numerous preclinical studies. … CG0070 is investigated in clinical trials for treating bladder cancer. CG0070 is a solid.
ATHX-105
go.drugbank.com/drugs/DB06008InvestigationalATHX-105 is an investigational selective 5HT2c receptor agonist developed by Athersys Inc. for the treatment of Obesity.
Aprocitentan
go.drugbank.com/drugs/DB15059ApprovedInvestigationalEndothelin receptor antagonism provides a novel therapeutic pathway for the management of patients with resistant hypertension. … [A263386] Patients with resistant hypertension are at an increased risk of cardiovascular and renal events[A263386] and have traditionally had limited additional treatment options.
Categories: Endothelin Receptor Antagonists, P-glycoprotein substrates