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Rituximab
go.drugbank.com/drugs/DB00073ApprovedInvestigationalFDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however, has now been approved for a variety of conditions [FDA label]. … The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences [A40017], [FDA label].
Categories: Biologics for Rheumatoid Arthritis TreatmentProducts: Mabthera Concentrate for Solution for Infusion 100mg/10ml, TRUXIMA® CONCENTRATE FOR SOLUTION FOR INFUSION 10MG/MLTeriparatide
go.drugbank.com/drugs/DB06285ApprovedInvestigational[A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595]
Products: FORTEO 250 UG SOLUTION FOR INJECTION, KAULIV 20 micrograms/80 microliters solution for injectionSulfur hexafluoride
go.drugbank.com/drugs/DB11104ApprovedInvestigationalSulfur hexafluoride is an ultrasound contrast agent indicated for use •in echocardiography to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border … in adult patients with suboptimal echocardiograms •in ultrasonography of the liver for characterization of focal liver lesions in adult and pediatric patients
Products: SONOVUE POWDER FOR DISPERSION FOR INJECTION 8 microlitres/mlTimolol
go.drugbank.com/drugs/DB00373ApprovedInvestigational[L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management of conditions such as open-angle glaucoma and hypertension. … Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes.
Mixtures: Van-dorzolamide-timolol, Cosopt PFCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesZinc gluconate
go.drugbank.com/drugs/DB11248ApprovedInvestigationalVet approvedStudies show that zinc may be better absorbed in humans in the gluconate form [A32412], [L2105], however, results from other studies may vary. … Studies suggest that administration of zinc along with new low osmolarity oral rehydration solutions/salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for
Mixtures: PEDIALYTE ® MAX 60 MEQ CON ZINC, Cal-mag Vitamin C and Zinc TabCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseGemcitabine
go.drugbank.com/drugs/DB00441ApprovedInvestigationalIt was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers.
Categories: P-glycoprotein substrates, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: Gemzar 1 g Pulver zur Herstellung einer Infusionslösung, Gemzar 200 mg Pulver zur Herstellung einer InfusionslösungCholecalciferol
go.drugbank.com/drugs/DB00169ApprovedInvestigationalNutraceuticalHowever, studies are also ongoing to determine whether or not cholecalciferol may also play certain roles in cancer, autoimmune disorders, cardiovascular disease, and other medical conditions that may … forms of vitamin d and are found in various types of food for daily intake [L5689].
Mixtures: Multivitamins and Minerals for Men, Multivitamins and Minerals for Young MenCategories: Drugs for Treatment of Bone Diseases, Cytochrome P-450 SubstratesGalcanezumab
go.drugbank.com/drugs/DB14042ApprovedInvestigational[A33112] Galcanezumab was approved by the FDA in September 2018, and is indicated for the preventive treatment of migraine and the treatment of episodic cluster headache. … [L42060] It is unknown if galcanezumab has an effect on pregnancy outcomes. A pregnancy exposure registry has been established to evaluate the safety of this drug in pregnant women.[L42060]
Categories: Calcitonin Gene-Related Peptide Receptor AntagonistsProducts: EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED PEN 120 MG/ML, Pontevia 120 mg solution for injection in pre-filled penVedolizumab
go.drugbank.com/drugs/DB09033ApprovedInvestigational[L48216] Vedolizumab was developed by Takeda and approved by the FDA under the brand name ENTYVIO for the maintenance therapy of moderately to severely active Ulcerative Colitis and Crohn’s Disease … however, the selective activity of vedolizumab against α4β7 integrin has been thought to contribute to its more favorable safety profile compared to its predecessor natalizumab, the first integrin receptor
Categories: Integrin Receptor AntagonistProducts: Entyvio 300mg Powder for Concentrate for Solution for Infusion, ENTYVIO POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 300MG/VIALTuroctocog alfa
go.drugbank.com/drugs/DB09109ApprovedTuroctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally
Products: NovoEight 500IU Powder and Solvent for Solution for Injection, NovoEight 1000IU Powder and Solvent for Solution for Injection