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Voriconazole
go.drugbank.com/drugs/DB00582ApprovedInvestigationalThe increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some [fluconazole]-resistant organisms.
Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic UseProducts: VFEND (200 MG POWDER FOR SOLUTION FOR INFUSION, Voriconazole-AFT 200 mg powder for solution for infusionOseltamivir
go.drugbank.com/drugs/DB00198ApprovedInvestigational[A180574, L7267, A180580] However, antiviral treatment might be beneficial when initiated after 48 hours for patients with severe, complicated or progressive illness or for hospitalized patients. … Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseProducts: FLUHALT FOR ORAL SUSPENSION 60 mg/ 5 ml, Oseltamivir Phosphate for Oral SuspensionDexrazoxane
go.drugbank.com/drugs/DB00380ApprovedInvestigationalWithdrawn[PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy.
Categories: Detoxifying Agents for Antineoplastic TreatmentProducts: Dexrazoxane for InjectionFosaprepitant
go.drugbank.com/drugs/DB06717ApprovedInvestigationalFosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Categories: Neurokinin-1 Receptor Antagonists, Substance P/Neurokinin-1 Receptor AntagonistProducts: Powder for Solution for Infusion 150mg, Fosaprepitant for InjectionCarbetocin
go.drugbank.com/drugs/DB01282ApprovedInvestigationalCarbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Products: DURATOCIN RTS SOLUTION FOR INJECTION 100 MCG/ML, Pharmidea Carbetocin 100 microgram/ml solution for injectionPotassium chloride
go.drugbank.com/drugs/DB00761ApprovedInvestigationalWithdrawnThe FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release … dosage forms and those products formulated for preparation of solution prior to ingestion.
Mixtures: FORTRANS FOR ORAL SOLUTION, KABIVEN EMULSION FOR INFUSIONProducts: Potassium Chloride for Oral Solution, Potassium Chloride for Hemodialysis 7.55Peginterferon alfa-2a
go.drugbank.com/drugs/DB00008ApprovedInvestigational-2a for the treatment of Hepatitis C [A19593]. … When combined together, Peginterferon alfa-2a and [DB00811] have been shown to achieve a SVR between 36% for genotype 1 and 59% for genotypes 2-6 after 48 weeks of treatment.
Categories: Treatments for Hepatitis CProducts: PEGASYS PRE-FILLED SYRINGE FOR INJECTION 180 mcg/0.5 ml, PEGASYS PRE-FILLED SYRINGE FOR INJECTION 135 mcg/0.5 mlGadoteridol
go.drugbank.com/drugs/DB00597ApprovedInvestigational[A263076] Initially approved by the FDA in 1992, gadoteridol received additional approval in 2020 for use in pediatric patients less than 2 years old.[L49876]
Products: ProHance 279.3 mg/ml solution for injectionNusinersen
go.drugbank.com/drugs/DB13161ApprovedInvestigationalFDA in December, 2016 as Spinraza for the treatment of children and adults with spinal muscular atrophy (SMA). It is adminstrated as direct intrathecal injection.
Products: Spinraza 12 mg Solution for InjectionExametazime
go.drugbank.com/drugs/DB11179ApprovedIt acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex. … Exametazime is a diagnostic radiopharmaceutical agent commonly used for the preparation of Tc99m Exametazime injection.
Products: CERETEC FOR INJECTION 0.5 mg/vial