Search

Displaying results 371 - 380 of 9431 in total
  1. Drug

    Barzolvolimab

    go.drugbank.com/drugs/DB18934
    Investigational

    Barzolvolimab is under investigation in clinical trial NCT06455202 (A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)).

    Synonyms: Immunoglobulin G1 [233-alanine,234-glutamine,251-tyrosine,253-threonine,255-glutamic acid,321-glutamine,de-C-terminal-lysine], anti-(human receptor tyrosine kinase KIT extracellular domain) (human-Mus
  2. Drug

    Heparin

    go.drugbank.com/drugs/DB01109
    ApprovedInvestigational

    Furthermore, the effects of UH can typically be reversed by using protamine sulfate. … It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa.

    Products: EPARINA CALCICA TS, FUCOCUX GEL 50000 IE
  3. Drug

    Omidenepag isopropyl

    go.drugbank.com/drugs/DB15071
    Approved

    [A253263,A253268] Prostanoid FP receptor agonists (FP agonists), such as [latanoprost], are part of the first-line therapy for ocular hypertension and primary open-angle glaucoma; however, not all patients … The use of an EP2 receptor agonist such as omidenepag represents an alternative in these scenarios. Omidenepag IOP-lowering effect is comparable to the one observed with [latanoprost].

    Categories: Receptors, Prostaglandin E, EP2 Subtype, agonists
  4. Drug

    Peppermint oil

    go.drugbank.com/drugs/DB11198
    ApprovedInvestigational

    The use of peppermint oil in the management of irritable bowel syndrome (IBS) has been investigated in many clinical studies due to its relaxing effects on smooth muscle; however the evidence supporting … , thereby facilitating its effect in the lower GI tract without effects in the upper tract [A33055].

    Mixtures: HO YAN HOR MEDICATED OIL, Sinsinpap HotProducts: Esprit De Menthe Poivref
  5. Drug

    Thiamine

    go.drugbank.com/drugs/DB00152
    ApprovedInvestigationalNutraceuticalVet approved

    Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. … Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.

    Mixtures: Folika-T, TL-Folate
  6. Drug

    Sodium chloride

    go.drugbank.com/drugs/DB09153
    ApprovedInvestigationalVet approved

    Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines. … Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.

    Mixtures: GaviLyte - C TM, Gavilyte G TmProducts: Breathe the Sea All-Natural Seawater, SOLUCION DE CLORURO DE SODIO INYECTABLE
  7. Drug

    Fordadistrogene movaparvovec

    go.drugbank.com/drugs/DB16800
    Investigational

    Synonyms: DNA (RECOMBINANT ADENO-ASSOCIATED VIRUS 9 VECTOR PF-06939926 HUMAN MUSCLE-SPECIFIC ENHANCER/PROMOTER PLUS HUMAN MINI-DYSTROPHIN GENE PLUS ADENO-ASSOCIATED VIRUS 9 INVERTED TERMINAL REPEAT FLANKS)
  8. Drug

    Chymotrypsin

    go.drugbank.com/drugs/DB09375
    ApprovedInvestigationalVet approvedWithdrawn

    Chymotrypsin contains both the catalytic triad and oxyanion hole, and the tertiary structure of chymotrypsin is similar to [DB11237] [A32642]. … Chymotrypsin is the most abundant pancreatic proteases that represent up to 10-20% of the total protein synthesized by the exocrine pancreas [A32637].

  9. Drug

    PCO-371

    go.drugbank.com/drugs/DB14946
    Investigational

    PCO-371 is under investigation in clinical trial NCT02475616 (A Single Ascending Dose Study of PCO371 in Healthy Volunteers).

    Synonyms: non-peptide small molecule orally available agonist of the parathyroid hormone receptor type I
  10. Drug

    Botaretigene sparoparvovec

    go.drugbank.com/drugs/DB16814
    Investigational

    Synonyms: VIRUS 5 VECTOR AAV-RPGR HUMAN RHODOPSIN KINASE PROMOTER FRAGMENT-REGULATED HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR RPGR-ORF15 ISOFORM GENE VARIANT PLUS ADENO-ASSOCIATED VIRUS 2 INVERTED TERMINAL REPEAT