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Rice bran oil
go.drugbank.com/drugs/DB11293ApprovedInvestigationalRice bran oil is classified as an indirect additive used in food contact substances by the FDA.
Butyrylthiocholine
go.drugbank.com/drugs/DB04250ExperimentalA sulfur-containing analog of butyrylcholine which is hydrolyzed by butyrylcholinesterase to butyrate and thiocholine. It is used as a reagent in the determination of butyrylcholinesterase activity.
Brecanavir
go.drugbank.com/drugs/DB04887InvestigationalBrecanavir (VX-385) an orally active aspartic protease inhibitor (PI), under investigation by Vertex and GlaxoSmithKline for the treatment of HIV. … In December of 2006 GSK announced a decision to discontinue the development of brecanavir for the treatment of HIV. The decision was based on issues regarding the formulation of the drug.
Difluprednate
go.drugbank.com/drugs/DB06781ApprovedInvestigationalDifluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. Difluprednate is abbreviated DFBA, or diflu...
Diazepinomicin
go.drugbank.com/drugs/DB12420InvestigationalDiscovered using Thallion’s DECIPHER technology, diazepinomicin has completed preclinical studies conducted by the National Cancer Institute and Thallion to establish safety and efficacy in animal and … Diazepinomicin is a natural product derived from a non-pathogenic micro-organism.
Oglufanide
go.drugbank.com/drugs/DB05779InvestigationalOglufanide works as a regulator of the body's immune response, is being given by intranasal administration to patients with chronic hepatitis C viral infection. … being acquired by Implicit Bioscience in 2005.
CZEN 002
go.drugbank.com/drugs/DB05479ExperimentalThe antimicrobial activity of CZEN-002 is unique in that it does not depend on direct damage to the microbial membrane. … It appears that CZEN-002 works on a receptor in yeast that has yet to be identified.
Sodium aurothiomalate
go.drugbank.com/drugs/DB09276ApprovedWithdrawnIt is most effective in active progressive rheumatoid arthritis and of little or no value in the presence of extensive deformities or in the treatment of other forms of arthritis.
Yohimbine
go.drugbank.com/drugs/DB01392ApprovedInvestigationalVet approvedWithdrawnIt is also alleged to be an aphrodisiac.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeAD 337
go.drugbank.com/drugs/DB05725InvestigationalThe drug was created by Sosei pharmaceuticals to treat Fibromyalgia in female patients. … AD 337 was under investigation in clinical trial NCT00377039 (A Multicentre Trial to Determine the Efficacy and Safety of AD-337 in the Treatment of Fibromyalgia).