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Safrazine
go.drugbank.com/drugs/DB09253ApprovedWithdrawnSafrazine is a member of the hydrazine family with non-selective and irreversible inhibitor effects against monoamine oxidases. In 1960, it was used as an antidepressant but it is now discontinued.
Categories: Monoamine Oxidase Inhibitors, Non-Selective, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeRPI-78M
go.drugbank.com/drugs/DB05740ExperimentalRPI-78M is being developed for the treatment of multiple sclerosis (MS).
Amdinocillin
go.drugbank.com/drugs/DB01163ApprovedInvestigationalWithdrawnIt is poorly absorbed if given orally and is used in urinary infections and typhus. Amdinocillin is not available in the United States.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSynonyms: Penicillin HXGrapiprant
go.drugbank.com/drugs/DB12836InvestigationalVet approved[L4766] Grapiprant has been approved in March 2016 by the FDA's Center for Veterinary Medicine as a non-cyclooxygenase inhibiting NSAID for veterinary use.[A39836] … [A39838] This type of molecules is currently in development for veterinary patients.[A39816] This class of drugs was defined in 2013 by the World Health Organization.
Perospirone
go.drugbank.com/drugs/DB08922InvestigationalIt is commonly present as the hydrated hydrochloride salt form. … Dainippon Sumitomo Pharma developed perospirone in Japan in 2001 for the treatment of acute schizophrenia and bipolar mania as well as chronic schizophrenia.
Synonyms: cis-N-(4-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)butyl)-1,2-cyclohexanedicarboximideHydroxyethyl ethylcellulose
go.drugbank.com/drugs/DB14139ApprovedHydroxyethyl ethylcellulose modulates bacterial binding to salivary pellicle; moderately effective in preventing plaque formation.
Categories: Compounds used in a research, industrial, or household settingFlecainide
go.drugbank.com/drugs/DB01195ApprovedInvestigationalWithdrawn[A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. … [A186931] It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.
Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class IcSynonyms: N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamideHesperidin
go.drugbank.com/drugs/DB04703ApprovedInvestigationalHesperidin is a flavan-on glycoside found in citrus fruits.
Mixtures: NA, Rose Hips 500plus Nu LifeSynonyms: Hesperetin 7-O-rutinosideCefpiramide
go.drugbank.com/drugs/DB00430ApprovedCefpiramide is a third-generation cephalosporin antibiotic.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSertindole
go.drugbank.com/drugs/DB06144ApprovedWithdrawnIt has once again been approved and should soon be available on the French and Australian market. … It is a phenylindole derivative used in the treatment of schizophrenia.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome