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Bisacodyl
go.drugbank.com/drugs/DB09020ApprovedInvestigationalBisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. … [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300]
Synonyms: Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)Mixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET, Dyrax-Q TabZinc sulfate, unspecified form
go.drugbank.com/drugs/DB14548ApprovedZinc sulfate is a common zinc supplement in parenteral nutrition.[A216916,L12888]
Mixtures: i-Drops ARTIFICIAL TEARS, Se-Tan PLUSFlutamide
go.drugbank.com/drugs/DB00499ApprovedInvestigationalAn antiandrogen with about the same potency as cyproterone in rodent and canine species.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: α,α,α-trifluoro-2-methyl-4'-nitro-m-propionotoluidide, 4'-nitro-3'-trifluoromethylisobutyranilideAclidinium
go.drugbank.com/drugs/DB08897ApprovedIt has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012. … Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD).
Mixtures: DUAKLIR®GENUAIR®340/12MCG/DOSIS.Products: EKLIRA®GENUAIR® 322 MCG/DOSISPyrvinium
go.drugbank.com/drugs/DB06816ApprovedInvestigationalWithdrawnPyrvinium is an anthelmintic effective for pinworms. Several forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate, triflate and pamoate.
Categories: Heterocyclic Compounds, 2-RingSuvorexant
go.drugbank.com/drugs/DB09034ApprovedInvestigationalSuvorexant is a selective dual antagonist of orexin receptors OX1R and OX2R that promotes sleep by reducing wakefulness and arousal. It has been approved for the treatment of insomnia.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: BELSOMRA® 15 MG, BELSOMRA® 10 MGCyclandelate
go.drugbank.com/drugs/DB04838ApprovedWithdrawnCyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries. … A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEmbusartan
go.drugbank.com/drugs/DB19949ExperimentalEmbusartan is a small molecule drug. The usage of the INN stem '-sartan' in the name indicates that Embusartan is a angiotensin II receptor antagonist, antihypertensive (non-peptidic). … Embusartan has a monoisotopic molecular weight of 461.19 Da.
Categories: Angiotensin II Type 1 Receptor Blockers, Heterocyclic Compounds, 1-RingZalcitabine
go.drugbank.com/drugs/DB00943ApprovedWithdrawnA dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. … Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one, 2',3'-DideoxycytidinePhenacemide
go.drugbank.com/drugs/DB01121ApprovedPhenacemide is used to control certain seizures in the treatment of epilepsy. This medicine acts on the central nervous system (CNS) to reduce the number and severity of seizures.