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Tirapazamine
go.drugbank.com/drugs/DB04858InvestigationalIt is important to take into consideration that normally, the cells in these hypoxic regions are resistant to radiotherapy and most anticancer drugs. … For all these reasons, the combination of tirapazamine with other anticancer treatments is highly recommended.
Silver sulfadiazine
go.drugbank.com/drugs/DB05245ApprovedInvestigationalVet approvedSilver sulfadiazine is a sulfa derivative topical antibacterial used primarily on second- and third-degree burns.
Products: SULFADIAZINA DE PLATA, SULFADIAZINA DE PLATA CREMAPhenprocoumon
go.drugbank.com/drugs/DB00946ApprovedInvestigationalWithdrawnCoumarin derivative that acts as a long-acting oral anticoagulant.
Bifemelane
go.drugbank.com/drugs/DB13550ExperimentalCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeCytisine
go.drugbank.com/drugs/DB09028InvestigationalCytisine is an alkaloid naturally derived from the Fabaceae family of plants including the genera Laburnum and Cytisus. … Recent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment than nicotine replacement therapy.
1D09C3
go.drugbank.com/drugs/DB05121ExperimentalThe antibody was isolated in collaboration with MorphoSys from its HuCAL(R) library of human antibodies. 1D09C3 binds to certain cell surface receptors, selectively killing activated, proliferating MHC … class II-positive tumor cells, which include those in B-cell and T-cell lymphomas. 1D09C3 has been shown to induce programmed cell death and does not require a functioning immune system for its cell-killing
Banoxantrone
go.drugbank.com/drugs/DB04975InvestigationalIt has been shown to work synergistically with fractionated radiation to significantly delay growth of tumours compared to administration of either banoxantrone or radiation alone. … Banoxantrone is a highly selective bioreductive drug that is activated in, and is preferentially toxic to, hypoxic cells in tumours.
Orgotein
go.drugbank.com/drugs/DB11444ExperimentalVet approvedHydrogen peroxide can be degraded by catalase. The antioxidant mechanism of SOD is common to most organisms exposed to oxygen. A notable exception is Lactobacillus plantarum. … Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation of the superoxide radical into either the less damaging hydrogen peroxide or molecular oxygen.
Volixibat
go.drugbank.com/drugs/DB13914InvestigationalIf approved for use, it will be the first available agent for the treatment of NASH. … According to Shire, the pharmaceutical manufacturer of Volixibat, it has been granted fast track status by the Food and Drug Administration due to promising initial results and a need for therapeutic treatments