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Pentostatin
go.drugbank.com/drugs/DB00552ApprovedInvestigationalA potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexCositecan
go.drugbank.com/drugs/DB05806InvestigationalIt has been developed for superior oral bioavailability and increased lactone stability. It is used to treat cancer.
Cytisine
go.drugbank.com/drugs/DB09028InvestigationalAlso known as baptitoxine or sophorine, cytisine has been used as a smoking cessation treatment since 1964, and is relatively unknown in regions outside of central and Eastern Europe. … Cytisine is an alkaloid naturally derived from the Fabaceae family of plants including the genera Laburnum and Cytisus.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceBuformin
go.drugbank.com/drugs/DB04830ApprovedWithdrawnIt was withdrawn from the market in most countries due to a high risk of causing lactic acidosis. … Buformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin.
Categories: Drugs Used in DiabetesAtractylodes japonica root oil
go.drugbank.com/drugs/DB11270ApprovedWithdrawnIt is present in some cosmetic products such as whitening creams as an active ingredient and lubricant for skin irritation. … Atractylodes japonica root oil is obtained from the roots of Atractylodes japonica, which is a herb native to eastern Asia.
DTS-201
go.drugbank.com/drugs/DB06071ExperimentalDTS-201 is a prodrug of doxorubicin, a widely used anti-cancer drug that Diatos intends to develop for the treatment of various solid tumors. It is activated in the tumor environment. … express high levels of CD-10* or TOP** peptidases, such as prostate cancer, colorectal cancer, melanoma, pancreatic cancer and some types of renal cancer.
Phenmetrazine
go.drugbank.com/drugs/DB00830ApprovedIllicitA sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine.
Tricaine
go.drugbank.com/drugs/DB11552ExperimentalVet approvedIt is also the only anesthetic licensed in the United States for use in fin fish that are intended for human consumption. … Tricaine (as tricaine methanesulfonate) is white powder used for anesthesia, sedation, or euthanasia of fish.
Cat dander extract
go.drugbank.com/drugs/DB13904ApprovedIt is used in the diagnosis and treatment (immunotherapy) of patients with a history of allergy to cats. … Cat dander extract is either subcutaneously or intracutaneously administered and contains dry cat dander or dry defatted cat pelt.