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D-Tryptophan
go.drugbank.com/drugs/DB03225ExperimentalThe distinguishing structural characteristic of tryptophan is that it contains an indole functional group. It is an essential amino acid as defined by its growth effects on rats. … It is encoded in the standard genetic code as the codon UGG. The D-stereoisomer is occasionally found in naturally produced peptides (for example, the marine venom peptide contryphan).
Loprazolam
go.drugbank.com/drugs/DB13643ExperimentalIt is a positive modulator of GABA-A receptor that enhances the inhibitory neurotransmission. It is not an FDA-approved drug. … It is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent nocturnal awakenings.
Lutetium Lu 177 dotatate
go.drugbank.com/drugs/DB13985ApprovedInvestigationalIt is a first radiopharmaceutical agent to be approved for gastroenteropancreatic neuroendocrine tumors (GEP-NETs) and is indicated for adult patients with somatostatin receptor-positive GEP-NETs [L1191 … In a clinical trial involving patients with advanced somatostatin receptor-positive GEP-NET, the treatment of Lutetium Lu 177 dotatate in combination with octreotide resulted in longer progression-free
KT-253
go.drugbank.com/drugs/DB18487InvestigationalKT-253 is a selective heterobifunctional small molecule degrader of mouse double minute 2 (MDM2).
Trenonacog alfa
go.drugbank.com/drugs/DB13201InvestigationalHuman coagulation factor IX (EC 3.4.21.22, Christmas factor, plasma thromboplastin component), produced in CHO cells.
Motexafin gadolinium
go.drugbank.com/drugs/DB05428InvestigationalIt belongs to the family of drugs called metalloporphyrin complexes. Also called gadolinium texaphyrin. … It may make tumor cells more sensitive to radiation therapy, improve tumor images using magnetic resonance imaging (MRI), and kill cancer cells.
MM-093
go.drugbank.com/drugs/DB05512InvestigationalResearch on AFP suggests that it may play a role in modulating the immune system of the mother in order to protect the developing fetus during pregnancy. … MM-093 is a recombinant version of human alpha-fetoprotein (hAFP), an immunomodulatory serum protein normally produced at very high levels by the fetus and present in low levels in the blood of adults