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Displaying results 3841 - 3850 of 9670 in total
  1. Drug

    Synthetic Conjugated Estrogens, B

    go.drugbank.com/drugs/DB09318
    Approved

    There is currently no generic form of CEEs available as a detailed analytical characterization of the active ingredients or of their estrogenic activity is not available at this time. … Conjugated Equine Estrogens (CEEs) are derived from the urine of pregnant mares and contain a blend of at least 10 estrogen derivatives.

  2. Target

    Annexin A2

    go.drugbank.com/bio_entities/BE0001170
    TargetHumans

    Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degra...

    Synonyms: PAP-IV
  3. Drug

    NS-398

    go.drugbank.com/drugs/DB14060
    Experimental

    It was developed as part of the mechanistic study of the cyclooxygenases.

  4. Drug

    Ecallantide

    go.drugbank.com/drugs/DB05311
    Approved

    It was discovered by phage display technology [A32017]. … Apart from its FDA and EMA indication, ecallantide has been used off label in the management of nonhistaminergic angioedema, not due to HAE [A32017].

  5. Drug

    Rexin G

    go.drugbank.com/drugs/DB16450
    Investigational

    It is under development by Epeius Biotechnologies for the potential treatment of metastatic cancer. It is also being investigated for preventing SARSCOV-2 viral entry.

  6. Drug

    ZEN-012

    go.drugbank.com/drugs/DB06042
    Experimental

    ZEN-012 also expresses additional modes of action such as pro-apoptotic and anti-angiogenic properties. It is developed for the treatment of solid tumors.

  7. Drug

    Olesoxime

    go.drugbank.com/drugs/DB05185
    Investigational

    For example, it has demonstrated the ability to prevent neurodegeneration, enhance nerve function and accelerate neuroregeneration following nerve trauma.[A3282,A253233] … Olesoxime is a cholesterol-like small molecule that has demonstrated a remarkable neuroprotective profile in a battery of both in vitro and in vivo preclinical models.

    Synonyms: (EZ)-N-(CHOLEST-4-EN-3-YLIDENE)HYDROXYLAMINE, cholest-4-en-3-one, oxime
  8. Drug

    RS5441

    go.drugbank.com/drugs/DB33178
    Experimental

    RS5441, also known as ET-02, is a small molecule topical medication investigated for male pattern baldness and age-related alopecia.[L57508, L57509]

  9. Drug

    Pardoprunox

    go.drugbank.com/drugs/DB12061
    Investigational

    Pardoprunox has been used in trials studying the treatment of Early Stage Parkinson's Disease and Advanced Stage Parkinson's Disease.

  10. Drug

    Vasomera

    go.drugbank.com/drugs/DB16498
    Investigational