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Lycopene
go.drugbank.com/drugs/DB11231ApprovedLycopene is a non-essential human nutrient that is classified as a non-provitamin A carotenoid pigment since it lacks a terminal beta-ionone ring [A27242] and does not mediate vitamin A activity.
Valoctocogene roxaparvovec
go.drugbank.com/drugs/DB15561ApprovedInvestigationalWithdrawnIt is not approved for use in the United States.
Tegafur
go.drugbank.com/drugs/DB09256ApprovedInvestigationalIt is a pyrimidine analogue used in combination therapies as an active chemotherapeutic agent in conjunction with [DB09257] and [DB03209], or along with [DB00544] as [DB09327].
Pretomanid
go.drugbank.com/drugs/DB05154ApprovedInvestigationalIt was the first TB drug developed by a nonprofit organization, known as TB Alliance, and was granted FDA approval on August 14, 2019.
Human interferon omega-1
go.drugbank.com/drugs/DB05472InvestigationalIt occurs naturally in the human body and is currently being manufactured by Intarcia through genetic engineering. … It has been investigated both in single and combination treatment. The biological activities of IFN-omega 1 and its physiological role are not known to date.
Tanaproget
go.drugbank.com/drugs/DB04787ExperimentalIt is currently in the process of being developed for clinical use as a contraceptive by Ligand Pharmaceuticals. … It is a high affinity, high efficacy agonist of the progesterone receptor (PR) with a much more selective binding profile relative to most conventional progestins.
PS386113
go.drugbank.com/drugs/DB05211ExperimentalIt is being developed by Schering-Plough and Pharmacopeia. Little information has been released about PS386113.
BBM-H901
go.drugbank.com/drugs/DB17704InvestigationalIt is being investigated for the treatment of hemophilia B.[A259048]
FB-101
go.drugbank.com/drugs/DB17956InvestigationalDeveloped by 1st Biotherapeutics, it is being investigated for the treatment of neurological disorders, such as Parkinson's Disease and amyotrophic lateral sclerosis (ALS).[L47102]
ARC183
go.drugbank.com/drugs/DB05124ExperimentalARC183 is a DNA aptamer, which is a single-stranded DNA molecule consisting of 15 deoxynucleotides that forms well-defined three-dimensional configuration, allowing it to bind to thrombin with high affinity … The key advantage of ARC183 compared to other thrombin inhibitors is its rapid onset of action and short half-life, giving it the potential to be an ideal agent for medical procedures that require rapid