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Omalizumab
go.drugbank.com/drugs/DB00043ApprovedInvestigational[A39518] Omalizumab was first approved in the US in 2003 [A263507] and in Europe in 2005. … By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its receptors on immune cells.
Categories: Amino Acids, Peptides, and ProteinsProducts: Xolair 150mg Powder and Solvent for Solution for Injection, XOLAIR 150MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONVasopressin
go.drugbank.com/drugs/DB00067ApprovedInvestigational[A228013] Despite a wide variety of functions, exogenous vasopressin is primarily used to control blood pressure during systemic shock by increasing vasoconstriction and renal fluid reuptake by acting … [A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids.
Categories: Vasopressin and Analogues, Amino Acids, Peptides, and ProteinsProducts: Vasopressin in 0.9% Sodium Chloride, VASOPRESINA 20 UI/MLCoagulation Factor IX Human
go.drugbank.com/drugs/DB13152ApprovedInvestigationalFactor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Synonyms: Factor IX (Human), Factor IX purificadoMixtures: OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU, Octaplex Powder and Solvent for Solution for InfusionEstradiol
go.drugbank.com/drugs/DB00783ApprovedInvestigationalVet approvedBecause it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain. … It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes.
Mixtures: FEMOSTON 1/10MG, FEMOSTON 1/10MGCategories: Pituitary and Hypothalamic Hormones and Analogues, Androgens and EstrogensIsosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigationalIt is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload. … [T28] First approved by the FDA in 1991,[L11743] isosorbide mononitrate is used for the prevention and management of angina pectoris caused by coronary artery disease; however, the onset of action of
Categories: Nitrates and Nitrites, Vasodilators Used in Cardiac DiseasesSynonyms: IS 5-MN, IS-5-MNDextran
go.drugbank.com/drugs/DB09255ApprovedInvestigationalVet approvedIt is administered by intravenous infusion. Dextran 75 is a complex branched glucan with an average molecular weight 75000 Daltons. … The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. The chains can be composed of about 200,000 glucose units.
Mixtures: Redness reliever and Lubricant, Meijer Advanced Redness and Irritation ReliefCategories: Compounds used in a research, industrial, or household setting, Blood and Related ProductsPetrolatum
go.drugbank.com/drugs/DB11058ApprovedInvestigationalIt is used as an ointment base, topical protectant, and lubricant.
Mixtures: Up and Up Diaper Rash, Up and Up HemorrhoidalCategories: Basic Ointments and Protectants, Compounds used in a research, industrial, or household settingAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalThe mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake. … An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia.
International brands: PK-MerzProducts: Endantadine Cap 100mg, Med-amantidine - Cap 100mgOrciprenaline
go.drugbank.com/drugs/DB00816ApprovedA beta-adrenergic agonist used in the treatment of asthma and bronchospasms. [PubChem]
Products: Alupent Syr 10mg/5.0ml, Alupent Liq 50mg/mlPaliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalPaliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. … It is available as an extended-release tablet, a once-monthly intramuscular injection, an every-three-month intramuscular injection, and a twice-yearly gluteal injection.[L16168,L37744,L4137,L37749]
Products: INVEGA Sustenna Prolonged Release Suspension for IM Injection 100mg/1.0ml, INVEGA Sustenna Prolonged Release Suspension for IM Injection 150mg/1.5ml