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Rupatadine
go.drugbank.com/drugs/DB11614ApprovedInvestigationalRupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesProducts: RUPATADINA EG, RUPAFIN® 10 MGLorazepam
go.drugbank.com/drugs/DB00186ApprovedInvestigationalLorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. … [A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977.
Synonyms: o-Chloroxazepam, o-ChlorooxazepamProducts: ATIVAN EXPIDET 1 MG TABLET, 50 ADET, ATIVAN EXPIDET 2.5 MG TABLET, 50 ADETRomiplostim
go.drugbank.com/drugs/DB05332ApprovedInvestigationalEach subunit consists of an IgG1 Fc carrier domain that is covalently attached to a polypeptide sequence that contains two binding domains to interact with thrombopoietin receptor c-Mpl. … Romiplostim is produced by recombinant DNA technology in Escherichia coli. FDA approved on August 22, 2008.
Products: NPLATE ® 500 MCG, NPLATE 500 MCG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADETPotassium citrate
go.drugbank.com/drugs/DB09125ApprovedInvestigationalVet approvedPotassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. … It contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis.
Mixtures: AQUALYTE ® 45 MEQ + ZINC SABOR FRESA. MANZANA Y UVA, POT-K 1,56 G EFERVESAN TABLET, 60 ADETProducts: CITRAL SYRUP (PLAIN) 500 mg/5 ml, UROCIT-K(5 MEQ) 540 MG 100 KONTROLLU SALIM TABLETICaptopril
go.drugbank.com/drugs/DB01197ApprovedInvestigationalCaptopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Mixtures: CAPOZIDE 50/25 MG TABLETAS, CAPTOPRIL E IDROCLOROTIAZIDE HEXALCategories: P-glycoprotein inhibitorsFlutamide
go.drugbank.com/drugs/DB00499ApprovedInvestigationalAn antiandrogen with about the same potency as cyproterone in rodent and canine species.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: α,α,α-trifluoro-2-methyl-4'-nitro-m-propionotoluidide, 4'-nitro-3'-trifluoromethylisobutyranilideBimatoprost
go.drugbank.com/drugs/DB00905ApprovedInvestigational[L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug … Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form.
Mixtures: BIMATOPROST E TIMOLOLO EG, BIMATOPROST E TIMOLOLO EGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEfavirenz
go.drugbank.com/drugs/DB00625ApprovedInvestigationalEfavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human … immunodeficiency virus (HIV) type 1.
Mixtures: Efatriten 600 mg/200 mg/245 mg Filmtabletten, Padviram 600 mg/200 mg/245 mg - FilmtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersApomorphine
go.drugbank.com/drugs/DB00714ApprovedInvestigational[A203597,A203618] Apomorphine was granted FDA approval on 20 April 2004.[L13919] … [A203618] Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and a treatment of other movement disorders.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol, (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diolKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigational[L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511] … Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.
Mixtures: Ixoba M, Dex-Moxi-KetorCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates