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Displaying results 381 - 390 of 10000 in total
  1. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0001265
    Target

    Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. … Gag-Pol polyprotein Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol
  2. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0001342
    Target

    Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. … Gag-Pol polyprotein Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol
  3. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0001732
    TargetHIV-2

    Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. … Gag-Pol polyprotein Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol
  4. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0004855
    TargetHuman immunodeficiency virus 1

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol
  5. Drug

    Ibuprofen

    go.drugbank.com/drugs/DB01050
    ApprovedInvestigational

    [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. … [A39076] On the available products, ibuprofen is administered as a racemic mixture.

    Mixtures: MULTIDOL® NOCHE, NORAVER®G FAST TOTAL NOCHE.Categories: Topical Products for Joint and Muscular Pain, Experimental Unapproved Treatments for COVID-19
  6. Drug

    Morphine

    go.drugbank.com/drugs/DB00295
    ApprovedInvestigational

    [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. … [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine

    Products: GRATEN LI, Morphine Lp Epidural
  7. Drug

    Irinotecan

    go.drugbank.com/drugs/DB00762
    ApprovedInvestigational

    Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of [camptothecin], which is extracted from the Chinese tree _Camptotheca acuminate_. … [L50186] The active metabolite SN-38 is also a potent inhibitor of DNA topoisomerase I.

    Categories: UGT1A1 Substrates with a Narrow Therapeutic Index, UGT1A9 Substrates with a Narrow Therapeutic IndexProducts: DARITEX-A, IRINOTECAN SOLUCIÓN PARA INYECCION VIAL POR 100 MG/5 ML
  8. Drug

    Insulin human

    go.drugbank.com/drugs/DB00030
    ApprovedInvestigational

    Unfortunately, limited uptake by physicians and patients, poor sales, bulky packaging, and concerns over the possible impact on lung cancer development resulted in Exubera products being withdrawn from … If left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening

    Mixtures: Mixtard® 30 100 IU/ml Suspension for Injection, Mixtard® 30 100 IU/ml Suspension for InjectionCategories: Insulins and Analogues for Injection, Fast-Acting
  9. Drug

    Fluoxetine

    go.drugbank.com/drugs/DB00472
    ApprovedInvestigationalVet approved

    Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). … [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies

    Categories: Antidepressive Agents Indicated for DepressionProducts: Pro-fluoxetine, FLUOXETIN AL 20MG TABL
  10. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0000787
    TargetHIV-1

    Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. … Gag-Pol polyprotein Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol