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Ranirestat
go.drugbank.com/drugs/DB05327InvestigationalIt has been used in trials studying the treatment of Mild to Moderate Diabetic Sensorimotor Polyneuropathy. … Ranirestat is a structurally novel and stereospecifically potent aldose reductase (AKR1B; EC 1.1.1.21) inhibitor, which contains a succinimide ring that undergoes ring-opening at physiological pH levels
Methylpropylpropanediol dinitrate
go.drugbank.com/drugs/DB13408ExperimentalCategories: Vasodilators Used in Cardiac DiseasesOMS-103HP
go.drugbank.com/drugs/DB05303InvestigationalOMS103HP is the first drug being developed to improve joint function following arthroscopic surgery, one of the most common procedures performed today by orthopedic surgeons.
Amitraz
go.drugbank.com/drugs/DB11373ExperimentalVet approvedAmitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. … Amitraz presents a lower effect in mammals and thus, it is widely used in the treatment of mite- or tick-infestation of dogs.
Categories: Compounds used in a research, industrial, or household settingTalizumab
go.drugbank.com/drugs/DB05797ExperimentalTNX-901 is a therapeutic monoclonal antibodies designed to address significant unmet medical needs in the areas of asthma, allergy, inflammation and other diseases affecting the human immune system.
Alkaline Phosphatase
go.drugbank.com/drugs/DB05768InvestigationalAP only acts locally in the colon to reduce the continuous inflammation of the colon by endotoxin from Gram-negative bacteria and extracellular ATP in UC patients. … Alkaline Phosphatase (AP) is an oral treatment and has a very favorable side-effect profile.
Tanespimycin
go.drugbank.com/drugs/DB05134InvestigationalIt is developed for the treatment of several types of cancer, solid tumors or chronic myelogenous leukemia. … Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90).
R1295
go.drugbank.com/drugs/DB05122ExperimentalR1295 is an integrin antagonist currently in clinical trials for the treatment of rheumatoid arthritis. … Integrins are associated to the pathology seen in some of the autoimmune diseases such as rheumatoid arthritis.
Rufloxacin
go.drugbank.com/drugs/DB13772InvestigationalRufloxacin is a quinolone antibiotic.[A31894]
Categories: Topoisomerase II InhibitorsNP2
go.drugbank.com/drugs/DB06308InvestigationalIt was under investigation in clinical trial NCT01291901 (NP2 Enkephalin For Treatment of Intractable Cancer Pain). … NP2 is a replication defective HSV-1 based gene transfer vector engineered to express human preproenkephalin.