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Displaying results 3911 - 3920 of 10000 in total
  1. Drug

    Vindesine

    go.drugbank.com/drugs/DB00309
    ApprovedInvestigationalWithdrawn

    Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  2. Drug

    AstraZeneca COVID-19 Vaccine

    go.drugbank.com/drugs/DB15656
    ApprovedInvestigational

    [A192822,L12672] The ChAdOx1 nCoV-19 vaccine, produced in a partnership between The University of Oxford's Jenner Institute and Italian pharmaceutical manufacturer Advent Srl, consists of a replication-deficient … [L12672] The University of Oxford struck a development and distribution deal with AstraZeneca in May 2020[L32659] which paved the way for the vaccine's subsequent approval and usage in dozens of regions

  3. Drug

    Rolitetracycline

    go.drugbank.com/drugs/DB01301
    ApprovedWithdrawn

    A pyrrolidinylmethyl tetracycline.

    Synonyms: N-(Pyrrolidinomethyl)tetracycline, N-(1-Pyrrolidinylmethyl)-tetracycline
  4. Drug

    IPH 2101

    go.drugbank.com/drugs/DB06049
    Investigational

    IPH-2101 (NN-1975), a fully human monoclonal antibody developed for patients with acute myeloid leukemia.

  5. Drug

    TG-100801

    go.drugbank.com/drugs/DB05075
    Investigational

    TG100801 is a topically applied kinase inhibitor in macular degeneration patients. … It is administered noninvasively as an eye drop and is designed to suppress VEGF mediated leakage and additional kinase targets associated with inflammation, edema, and angiogenesis which are the pathological

  6. Drug

    Pranlukast

    go.drugbank.com/drugs/DB01411
    Investigational

    Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. … It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.

  7. Drug

    Aluminum zirconium pentachlorohydrate

    go.drugbank.com/drugs/DB11147
    Approved

    Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant agent.

    Products: On Duty 24 Hours Clear Protection Roll-On Anti-Perspirant Deodorant
  8. Drug

    NE-180

    go.drugbank.com/drugs/DB05619
    Experimental

    NE-180 was under investigation in a clinical trial conducted in the European Union.

  9. Drug

    Pirtobrutinib

    go.drugbank.com/drugs/DB17472
    ApprovedInvestigational

    Pirtobrutinib is a small molecule and a highly selective non-covalent inhibitor of Bruton’s tyrosine kinase (BTK). … treated with a covalent BTK inhibitor.

  10. Drug

    Grapiprant

    go.drugbank.com/drugs/DB12836
    InvestigationalVet approved

    [L4766] Grapiprant has been approved in March 2016 by the FDA's Center for Veterinary Medicine as a non-cyclooxygenase inhibiting NSAID for veterinary use.[A39836] … These molecules were derived from acylsulfonamide and are characterized to be a novel series of para-N-acylaminomethylbenzoic acid known to be prostaglandin receptor antagonists.