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Propacetamol
go.drugbank.com/drugs/DB09288Investigational[A32051] It is a derivative of [acetaminophen], or paracetamol, with the molecular formula glycine, N, N-diethyl-,4-(acetylamino)phenyl ester. … [A7892] It is not available in the United States but this prodrug has been widely used in other countries such as France since 1985.[L1505]
Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDSNirogacestat
go.drugbank.com/drugs/DB12005ApprovedInvestigationalIt was previously granted breakthrough therapy, fast track, and orphan drug designations for the treatment of desmoid tumors, and the final approval was based on positive results obtained in the Phase … Nirogacestat is a small-molecule gamma-secretase inhibitor that was investigated as a potential treatment for desmoid tumors.
LX1031
go.drugbank.com/drugs/DB05199InvestigationalLX1031 is designed to act locally in the gastrointestinal tract by reducing the serotonin available for receptor activation, without affecting serotonin levels in the brain or its central nervous system … LX1031 is an orally-dosed drug candidate for irritable bowel syndrome and other gastrointestinal disorders.
Rimexolone
go.drugbank.com/drugs/DB00896ApprovedWithdrawnRimexolone is a 1% eye drop solution is a glucocorticoid steroid. It is used to treat inflammation in the eye. It is marketed as Vexol.
Categories: Corticosteroids for Systemic Use, PlainAffitope AD01
go.drugbank.com/drugs/DB06086InvestigationalAffitope AD01 is an investigational drug developed for immunization to treat Alzheimer's Disease. … AD01 is a short peptide (7 amino acids in length) that induces Aß-targeting antibodies, therefore lowering Aß aggregates.
Pemoline
go.drugbank.com/drugs/DB01230ApprovedIllicitWithdrawnIn 2005, the Food and Drug Administration (FDA) withdrew approval for pemoline. In March 2005, Abbott Laboratories (Cylert marketer) had discontinued the production of Cylert arguing economic reasons.
Categories: Psychostimulants, Agents Used for ADHD and NootropicsCefpirome
go.drugbank.com/drugs/DB13682ApprovedCefpirome is a β-lactam or cephalosporin.[A249055]
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseRTA 744
go.drugbank.com/drugs/DB05920InvestigationalRTA 744 is a novel anthracycline derivative that crosses the blood-brain barrier and shows significant potential for the treatment of primary and metastatic brain cancers. … Anthracyclines are one of the most broadly used and effective classes of cancer therapies; however, they are not used to treat brain cancers because current therapies do not cross the blood-brain barrier
Riluzole
go.drugbank.com/drugs/DB00740ApprovedInvestigationalA glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. … Riluzole is marketed as Rilutek by Sanofi.
Categories: Compounds used in a research, industrial, or household settingProducts: RILUTEK® TABLETAS X 50MGAleglitazar
go.drugbank.com/drugs/DB08915InvestigationalIt is being investigated for use in patients with type II diabetes to reduce their risks of cardiovascular mortality and morbidity. … Aleglitazar is an agonist at the peroxisome proliferator-activated receptor (PPAR) for both the PPARα and PPARγ receptor subtypes.