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Candesartan
go.drugbank.com/drugs/DB13919InvestigationalCandesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of [candesartan cilexetil].
Categories: Angiotensin II receptor antagonists, Angiotensin II Type 2 Receptor BlockersSGN-15
go.drugbank.com/drugs/DB05818InvestigationalSGN-15 is studied in the treatment of cancer. It combines a monoclonal antibody with the anticancer drug doxorubicin. … Monoclonal antibodies are substances that are made in the laboratory and that can locate and bind to cancer cells. Doxorubicin is a type of anthracycline antitumor antibiotic.
Diacerein
go.drugbank.com/drugs/DB11994ApprovedInvestigationalWithdrawnIt is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including severe diarrhea [L780]. … Diacerein is a prodrug which is metabolized to rhein.
DG041
go.drugbank.com/drugs/DB05027ExperimentalIt block the formation of blood clots mediated through inflammation in atherosclerotic plaques but without increasing bleeding risk. … DG041 is a novel, first-in-class, orally-administered small molecule developmented for the prevention of arterial thrombosis and its complications.
Influenza B virus B/Darwin/7/2019 antigen (MDCK cell derived, propiolactone inactivated)
go.drugbank.com/drugs/DB15709ApprovedWithdrawnInactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
GTS-21
go.drugbank.com/drugs/DB05708InvestigationalGTS-21 has been studied in multiple Phase I studies in healthy volunteers and one Phase I/II study in schizophrenic patients. In all studies, the compound was well tolerated. … in human clinical trials.
Metrifonate
go.drugbank.com/drugs/DB11473ExperimentalVet approvedMetrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Categories: Compounds used in a research, industrial, or household settingResveratrol
go.drugbank.com/drugs/DB02709InvestigationalResveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. … However, studies find that Trans-resveratrol undergoes negligible oxidation in normal atmosphere at room temperature.
Categories: Compounds used in a research, industrial, or household settingIndigo
go.drugbank.com/drugs/DB16862InvestigationalCategories: Compounds used in a research, industrial, or household setting