Search
Antilymphocyte immunoglobulin (horse)
go.drugbank.com/drugs/DB09312ApprovedInvestigationalThe result is polyclonal IgG that is then purified from the horse's serum to produce a usable drug product that can be used for immunosuppression. … It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen.
Categories: Fluids and Secretions, Amino Acids, Peptides, and ProteinsProducts: Atgam Sterile Solution IV 50mg/ml, ATGAM 50MG/ML STERILE SOLUTION (5ML AMP)Suramin
go.drugbank.com/drugs/DB04786Investigational(From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Suramin is manufactured by Bayer in Germany as Germanin®. … A polyanionic compound with an unknown mechanism of action.
Categories: Agents Against Leishmaniasis and Trypanosomiasis, Antiparasitic Products, Insecticides and RepellentsLeptin
go.drugbank.com/drugs/DB05098Investigationalsignals from circulating leptin. … Thus, obesity develops when people take in more energy than they use over a prolonged period of time, and this excess food intake is not driven by hunger signals, occurring in spite of the anti-appetite
Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsZucapsaicin
go.drugbank.com/drugs/DB09120ApprovedWithdrawnZucapsaicin was approved by the Health Canada in 2010 as topical cream marketed under the brand name Zuacta but currently not FDA-approved. … These conditions include herpes simplex (HSV) infections, cluster headaches, migraine, and osteoarthritis of the knee.
Categories: Capsaicin and Similar Agents, Topical Products for Joint and Muscular PainCaspofungin
go.drugbank.com/drugs/DB00520ApprovedInvestigationalIt shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall. … Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc.
Categories: Amino Acids, Peptides, and ProteinsProducts: Cancidas Injection 50mg/vial, Cancidas Injection 70mg/vialSparteine
go.drugbank.com/drugs/DB06727ApprovedWithdrawnSparteine is a plant alkaloid derived from _Cytisus scoparius_ and _Lupinus mutabilis_ which may chelate calcium and magnesium. … Sparteine is not currently FDA-approved for human use, and its salt, sparteine sulfate, is one of the products that have been withdrawn or removed from the market for reasons of safety or effectiveness
Neurocognitive Disorders
go.drugbank.com/conditions/DBCOND0064252Drugs: ZuclopenthixolSynonyms: Dementia and Amnestic ConditionsDroxidopa
go.drugbank.com/drugs/DB06262ApprovedInvestigationalThe racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated in the treatment of orthostatic hypotension. … Chelsea Therapeutics obtained orphan drug status (ODS) for L-DOPS in the U.S. for NOH, and that of which associated with Parkinson's disease , pure autonomic failure, and multiple system atrophy, and is
Categories: Epinephrine and similars, Adrenergic and Dopaminergic AgentsAmdinocillin
go.drugbank.com/drugs/DB01163ApprovedInvestigationalWithdrawnIt is poorly absorbed if given orally and is used in urinary infections and typhus. Amdinocillin is not available in the United States.
Sulconazole
go.drugbank.com/drugs/DB06820ApprovedSulconazole nitrate, the active ingredient, is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes, making it an effective treatment for tinea cruris and tinea corporis … Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream and solution.
Categories: Imidazole and Triazole Derivatives