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BI 44370 TA
go.drugbank.com/drugs/DB16037InvestigationalBI 44370 TA is under investigation in clinical trial NCT00751803 (BI 44370 TA in Acute Migraine Attack).
Crotalus atrox antivenin
go.drugbank.com/drugs/DB13892ApprovedEach year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide. About 8000 of these snakebites involve venomous snake species. … Bites from this snake are the most common in the state of Texas, USA [A33157].
Temocapril
go.drugbank.com/drugs/DB08836InvestigationalTemocapril is a prodrug-type angiotensin-I converting enzyme (ACE) inhibitor not approved for use in the United States, but is approved in Japan and South Korea. … Temocapril can also be used in hemodialysis patients without risk of serious accumulation.
Categories: Agents Acting on the Renin-Angiotensin SystemCefroxadine
go.drugbank.com/drugs/DB11367ApprovedWithdrawnIt was used in Italy but has since been withdrawn. … Cefroxadine is an orally available cephalosporin antibiotic. As part of its drug class, it shares structural properties to [cefalexin] as well as its activity spectrum.
International brands: Cefthan-DSTransfluthrin
go.drugbank.com/drugs/DB15117InvestigationalTransfluthrin is under investigation in clinical trial NCT02394522 (Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM)).
Categories: Compounds used in a research, industrial, or household settingVarlitinib
go.drugbank.com/drugs/DB05944InvestigationalOver-expression of ErbB-2 and EGFR receptors in tumors is predictive of poor prognosis in cancer patients. … Varlitinib has shown significant anti-tumor activity in preclinical models of human breast, lung, and epidermal carcinoma tumors.
105AD7
go.drugbank.com/drugs/DB05113Investigational105AD7 is a human monoclonal antibody that mimics the complement regulatory protein, CD55, overexpressed by many solid tumours including osteosarcoma. 105AD7 induced antitumour inflammatory responses in … metastatic colorectal cancer patients. 105AD7 may be a suitable vaccine for treatment of this disease.
Culex pipiens
go.drugbank.com/drugs/DB14165ApprovedCulex pipiens allergenic extract is used in allergenic testing.
Sarocladium strictum
go.drugbank.com/drugs/DB14168ApprovedSarocladium strictum allergenic extract is used in allergenic testing.
ACA 125
go.drugbank.com/drugs/DB05489InvestigationalACA-125 mimics the tumor-associated antigen CA-125, which can be detected in about 80% of ovarian carcinomas. … To create ACA-125, a hybridoma cell was adapted to serum-free medium and antibody was produced in a hollow fiber cell culture system. Positive clinical results are now being reported.