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Growth arrest-specific protein 6
go.drugbank.com/bio_entities/BE0010201TargetHumansLigand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell su...
Synonyms: AXL receptor tyrosine kinase ligandTripeptidyl-peptidase 1
go.drugbank.com/bio_entities/BE0011158TargetHumansLysosomal serine protease with tripeptidyl-peptidase I activity (PubMed:11054422, PubMed:19038966, PubMed:19038967). May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysoso...
Synonyms: Cell growth-inhibiting gene 1 proteinHMI-203
go.drugbank.com/drugs/DB18520InvestigationalHMI-203 is an investigational gene therapy developed by Homology Medicines, Inc. … It consists of a recombinant adeno-associated virus (AAV) serotype HSC15 (rAAVHSC15) encoding human iduronate-2-sulfatase (hIDS).
RR001
go.drugbank.com/drugs/DB17369InvestigationalRR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand
Bimagrumab
go.drugbank.com/drugs/DB12584InvestigationalBimagrumab has been used in trials studying the treatment and supportive care of Sarcopenia, Skeletal Muscle, Mechanical Ventilation, Sporadic Inclusion Body Myositis, and Sporadic Inclusion Body Myositis
2-chloroethyl-3-sarcosinamide-1-nitrosourea
go.drugbank.com/drugs/DB11688Investigational2-chloroethyl-3-sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific
Synonyms: 2-chloroethyl-3-sarcosinamide-1-nitrosourea, ACETAMIDE, 2-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)METHYLAMINO)-Bemegride
go.drugbank.com/drugs/DB13740ExperimentalBemegride is a CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.
Categories: Heterocyclic Compounds, 1-RingNerve Growth Factor
go.drugbank.com/drugs/DB12620InvestigationalNerve Growth Factor has been used in trials studying the prevention and treatment of Mental Handicap, Alzheimer's Disease, Traumatic Brain Injury, Cerebral Palsy Children, and Delayed Speech Development
Sotrastaurin
go.drugbank.com/drugs/DB12369InvestigationalSotrastaurin has been used in trials studying the basic science and treatment of Uveal Melanoma, Richter Syndrome, Prolymphocytic Leukemia, Recurrent Mantle Cell Lymphoma, and Recurrent Small Lymphocytic
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingRivipansel
go.drugbank.com/drugs/DB12778InvestigationalRivipansel has been used in trials studying the other, basic science, and treatment of Pain Crisis, Renal impairment, Anemia, Sickle Cell, Sickle Cell Disease, and Sickle Cell Disorders, among others.