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Dihydroergocristine
go.drugbank.com/drugs/DB13345ApprovedDihydroergocristine is part of the ergoloid mixture products.[L2637] It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed by an alkaloid ergoline.
Categories: Ergot Alkaloids and DerivativesFlavin adenine dinucleotide
go.drugbank.com/drugs/DB03147Approved(Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency. … A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase.
Categories: Enzymes and Coenzymes, Nucleic Acids, Nucleotides, and NucleosidesBazedoxifene
go.drugbank.com/drugs/DB06401ApprovedInvestigationalIt is approved in the European Union (marketed in Italy and Spain) and Japan as monotherapy. … In 2013, the combination product containing conjugated estrogens and bazedoxifene was approved by the FDA for the treatment of moderate to severe vasomotor symptoms associated with menopause, as well as
Categories: Genito Urinary System and Sex Hormones, conjugated estrogens and bazedoxifeneBentiromide
go.drugbank.com/drugs/DB00522ApprovedWithdrawnBentiromide is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of supplemental pancreatic therapy. … It is typically administered orally. Cases of headache and gastrointestinal disturbances have been reported with the use of bentiromide. Bentiromide is currently not available in the U.S. or Canada.
Categories: Indicators and Reagents, Compounds used in a research, industrial, or household settingBebtelovimab
go.drugbank.com/drugs/DB16755ApprovedWithdrawnin the US. … [L40328] Bebtelovimab was issued an emergency use authorization (EUA) by the FDA on February 11, 2022, for the treatment of mild-to-moderate COVID-19 in select patients.
Categories: Amino Acids, Peptides, and ProteinsOmaveloxolone
go.drugbank.com/drugs/DB12513ApprovedInvestigational[A257529] In February 2023, omaveloxolone was approved by the FDA for the treatment of Friedreich's ataxia in adults and adolescents aged 16 years and older. … [L45424] The EMA approved this drug the following year, in February 2024, and Health Canada in March 2025 for the same condition.
Synonyms: Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-Serplulimab
go.drugbank.com/drugs/DB17451ApprovedInvestigationalSerplulimab is a humanized monoclonal IgG4 antibody that acts as an immune checkpoint inhibitor by targeting the programmed cell death-1 (PD-1) receptor. … It was first approved in China - where it is indicated for a number of different cancers[L52963] - and has since been approved in several southeast Asian countries.
Categories: Antineoplastic and Immunomodulating Agents, Monoclonal antibodies and antibody drug conjugatesTideglusib
go.drugbank.com/drugs/DB12129ApprovedInvestigationalWithdrawn[A31601] Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current status is withdrawn for the treatment of Alzheimer's disease as of 2012. … It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3).
Sulopenem etzadroxil
go.drugbank.com/drugs/DB16335ApprovedInvestigational[L51768] Sulopenem etzadroxil was approved by the FDA in October 2024 for the treatment of uncomplicated urinary tract infections. … [L51858] It is administered in combination with [probenecid] in order to increase antibiotic exposure.[L51768]
Patiromer
go.drugbank.com/drugs/DB09263ApprovedInvestigationalPatiromer sorbitex calcium is an amorphous, free-flowing powder that is composed of individual spherical beads. … Patiromer is a powder for suspension in water for oral administration, approved in the U.S. as Veltassa in October, 2015.
Categories: Compounds used in a research, industrial, or household setting, Potassium Ion Binding Activity