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Trimethyltetradecylammonium
go.drugbank.com/drugs/DB17342ExperimentalCategories: Compounds used in a research, industrial, or household setting3,4-Dihydroxycinnamic Acid
go.drugbank.com/drugs/DB01880InvestigationalCategories: Compounds used in a research, industrial, or household settingAminoethyl nitrate
go.drugbank.com/drugs/DB13585ExperimentalCategories: Vasodilators Used in Cardiac DiseasesETC-588
go.drugbank.com/drugs/DB05456ExperimentalIt is believed that the removal of cholesterol by ETC-588 through this pathway may result in the reversal of atherosclerosis. … and other lipids from cells including those in the arterial wall.
Dichlorvos
go.drugbank.com/drugs/DB11397ExperimentalVet approvedDichlorvos is found in urban waterways and its toxicity may impact humans, leading to poisoning, neurotoxicity, and cancer. … The compound has been available on the market since 1961 and its use is a controversial topic due to environmental and health concerns.
Categories: Compounds used in a research, industrial, or household settingLonidamine
go.drugbank.com/drugs/DB06266InvestigationalIn such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs. … Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK).
Trodusquemine
go.drugbank.com/drugs/DB06333InvestigationalIt has demonstrated the ability to stimulate regeneration of heart and multiple other tissues in animal models [A176600]. … Trodusquemine, a spermine metabolite of cholesterol, is a naturally occurring aminosterol that inhibits protein tyrosine phosphatase 1B.
Chlorzoxazone
go.drugbank.com/drugs/DB00356ApprovedIt is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
G207
go.drugbank.com/drugs/DB05827InvestigationalMediGene uses these viruses, however, in a modified and "disarmed" form in order to make them utilizable as a therapeutic agent in humans. … G207 is cancer-killing viruses, so-called oncolytic viruses, for the treatment of various forms of cancer developed by MediGene AG.
AZD-8330
go.drugbank.com/drugs/DB06061InvestigationalAZD-8330 is a potent, selective, orally active MEK inhibitor that blocks signal transduction pathways implicated in cancer cell proliferation and survival. … AZD-8330 has shown tumor suppressive activity in multiple preclinical models of human cancer including melanoma, pancreatic, colon, lung, and breast cancers.