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Troglitazone
go.drugbank.com/drugs/DB00197ApprovedWithdrawnIt was superseded by [pioglitazone] and [rosiglitazone].
Categories: Alimentary Tract and MetabolismRice bran oil
go.drugbank.com/drugs/DB11293ApprovedInvestigationalRice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. … Rice bran oil is classified as an indirect additive used in food contact substances by the FDA.
Telaprevir
go.drugbank.com/drugs/DB05521ApprovedWithdrawnIncivek has since been withdrawn from the market. … by 12 or 36 weeks of therapy with [DB00811], [DB00008], and [DB00022].
Categories: Amino Acids, Peptides, and ProteinsCefaloridine
go.drugbank.com/drugs/DB09008ApprovedWithdrawnIt is derived from cephalosporin C and is a zwitterion at physiological pH.
Deoxycholic acid
go.drugbank.com/drugs/DB03619ApprovedInvestigationalIt is marketed under the brand name Kybella by Kythera Biopharma and is the first pharmacological agent available for submental fat reduction, allowing for a safer and less invasive alternative than surgical … In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve aesthetic appearance and reduce facial fullness or convexity.
Categories: Bile Acids and Salts, Cholagogues and CholereticsAlicaforsen
go.drugbank.com/drugs/DB06224InvestigationalCategories: Nucleic Acids, Nucleotides, and NucleosidesFlucytosine
go.drugbank.com/drugs/DB01099ApprovedInvestigationalA fluorinated cytosine analog that is used as an antifungal agent.
Categories: Fluorouracil and prodrugsSafflower oil
go.drugbank.com/drugs/DB09446ApprovedInvestigationalWithdrawnExtracted from the seeds of safflowers, safflower oil is a rich source of various saturated fatty acids, monounsaturated fatty acid (oleic acid) or essential n-6 polyunsaturated fatty acid (PUFA) linoleic … Safflower oil is approved for use as an indirect additive in food contact substances and is readily available as a food ingredient.
Categories: Diet, Food, and NutritionMagnesium Aluminum Silicate
go.drugbank.com/drugs/DB11230ApprovedWithdrawnMagnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group [A32782]. … , and tablet binder.
Aminopterin
go.drugbank.com/drugs/DB08878ApprovedWithdrawnAminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia. … In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment of psoriasis.