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Displaying results 3961 - 3970 of 10000 in total
  1. Drug

    XL999

    go.drugbank.com/drugs/DB05014
    Investigational

    XL999 induces a cell-cycle block by a mechanism distinct from those previously identified and exhibits broad antitumor activity in xenograft models. … XL999 has the potential to prevent tumor growth — both directly by a novel effect on tumor cell proliferation and indirectly through inhibition of the host angiogenic response.

  2. Drug

    Sodium borate

    go.drugbank.com/drugs/DB14505
    Approved

  3. Drug

    Amorolfine

    go.drugbank.com/drugs/DB09056
    ApprovedWithdrawn

    It is not approved for the treatment of onychomycosis in the United States or Canada. … Amorolfine 5% nail lacquer in once or twice weekly applications is 60-71% effective in treating toenail onychomycosis; complete cure rates three months after stopping treatment (after six months of treatment

  4. Drug

    Alifedrine

    go.drugbank.com/drugs/DB20853
    Experimental

    The usage of the INN stem '-drine' in the name indicates that Alifedrine is a sympathomimetic. Alifedrine has a monoisotopic molecular weight of 289.2 Da.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Valinomycin

    go.drugbank.com/drugs/DB14057
    Experimental

    (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Allisartan isoproxil

    go.drugbank.com/drugs/DB18880
    Investigational

    Allisartan isoproxil is under investigation in clinical trial NCT03264352 (Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes).

    Categories: Agents Acting on the Renin-Angiotensin System
  7. Drug

    3-hydroxyanthranilic acid

    go.drugbank.com/drugs/DB03644
    Experimental

    An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    PPI-2458

    go.drugbank.com/drugs/DB05864
    Investigational

    In preclinical studies to date, PPI-2458 has demonstrated the potent pharmacologic activity of this class of compounds while displaying an improved pharmacokinetic and toxicity profile. … This class of compounds has been shown to prevent both abnormal cell growth and the formation of new blood vessels (known as angiogenesis), which contribute to the growth of aberrant tissues in diseases

  9. Drug

    Dengue virus serotype 1

    go.drugbank.com/drugs/DB22664
    Approved

    [L53368] Qdenga was approved for use in the European Union in December 2022.[L53373]

  10. Drug

    TM30339

    go.drugbank.com/drugs/DB05085
    Experimental

    TM30339 is an analogue of the natural hormone Pancreatic Polypeptide (PP), which is released in connection with meals. … TM30339 works through the same receptor as the natural satiety hormone, Pancreatic Polypeptide (PP), but TM30339 has improved properties compared with PP.