Valinomycin

DB14057ExperimentalSmall molecule

A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately... (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.

Formula / weight: C₅₄H₉₀N₆O₁₈ · 1111.338 g/mol (avg)
Also known as: Potassium ionophore I · Valinomicin
Code names: ANTIBIOTIC N-329 B · BRN 0078657

Resolves to

Compound

UNIIN561YS75MNCAS2001-95-8ChEMBLCHEMBL223643ChEBI28545

Structure

InChIKeyFCFNRCROJUBPLU-DNDCDFAISA-NSMILES

CC(C)[C@@H]1NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C

Transporters

O95342ABCB11P08183ABCB1

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2TransportersSubstrate / inhibitor direction, not just membership

Listed above

142Drug interactionsStructured to mechanism, not free text

9+ReferencesStructured and connected to the statements they support

Which companies are running trials of Valinomycin, in which indications and phases, and which of those programs are still active?

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