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GTI-2501
go.drugbank.com/drugs/DB05406ExperimentalGTI-2501 is a novel antisense drug which has shown a favorable safety profile in preclinical studies, and in a phase I clinical trial. … The drug is in a phase II clinical trial in combination with docetaxel for the treatment of hormone refractory prostate cancer.
Calcimycin
go.drugbank.com/drugs/DB19408InvestigationalIt binds to and transports calcium and other divalent cations across membranes, disrupts oxidative phosphorylation, and inhibits ATPase in rat liver mitochondria. … Primarily used as a biochemical tool for studying divalent cations in biological systems, Calcimycin also exhibits antibiotic activity against gram-positive bacteria and fungi.
Categories: Compounds used in a research, industrial, or household settingTheofibrate
go.drugbank.com/drugs/DB19587ExperimentalTheofibrate is a small molecule drug. The usage of the INN stem '-fylline' in the name indicates that Theofibrate is a N-methylated xanthine derivative. … The usage of the INN stem '-fibrate' in the name indicates that Theofibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.
Categories: Compounds used in a research, industrial, or household settingPivmecillinam
go.drugbank.com/drugs/DB01605ApprovedInvestigationalPivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. … It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
Lasalocid
go.drugbank.com/drugs/DB11423ExperimentalVet approvedLasalocid is an agent that presents antibacterial and coccidiostat activities. It is produced by strains of _Streptomyces lasaliensis_.
Categories: Compounds used in a research, industrial, or household settingBenzylpenicilloyl polylysine
go.drugbank.com/drugs/DB00895ApprovedInvestigationalThe quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluating allergic subjects. … Benzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy.
Delafloxacin
go.drugbank.com/drugs/DB11943ApprovedInvestigationalIt was approved in June 2017 under the trade name Baxdela for use in the treatment of acute bacterial skin and skin structure infections. … Delafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and basic science of Gonorrhea, Hepatic Impairment, Bacterial Skin Diseases, Skin Structure Infections,
Friulimicin B
go.drugbank.com/drugs/DB06087InvestigationalIt shows strong cidal activity against a number of Gram-positive pathogens which commonly cause serious infections in hospital patients and which are becoming more routinely acquired in the community. … Friulimicin B is a naturally occurring antibiotic produced by a micro-organism, *Actinoplanes friuliensis*.
Adenosine phosphate
go.drugbank.com/drugs/DB00131ApprovedInvestigationalNutraceuticalWithdrawnAdenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. … Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.[L43937]
Iolopride I-123
go.drugbank.com/drugs/DB20028ExperimentalIolopride I-123 is a small molecule drug. The usage of the INN stem '-pride' in the name indicates that Iolopride I-123 is a sulpiride derivative and analogue. … Iolopride I-123 has a monoisotopic molecular weight of 400.06 Da.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Iolopride i 123, Iolopride I-123