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Displaying results 3971 - 3980 of 10000 in total
  1. Drug

    Adenosine

    go.drugbank.com/drugs/DB00640
    ApprovedInvestigational

    [A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] … The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were not described in literature until the 1940s.

    Mixtures: Cellmov Cell Line Mask, Mizon Black Snail All In One Crea MCategories: Antiarrhythmics, Class V, Heterocyclic Compounds, 2-Ring
  2. Drug

    Canakinumab

    go.drugbank.com/drugs/DB06168
    ApprovedInvestigational

    It is expressed in a murine Sp2/0-Ag14 cell line and comprised of two 447- (or 448-) residue heavy chains and two 214-residue light chains, with a molecular mass of 145157 Daltons when deglycosylated. … Canakinumab is a recombinant, human anti-human-IL-1β monoclonal antibody that belongs to the IgG1/κ isotype subclass.

    Categories: Interleukin-1 BlockersProducts: IBECTA 150 MG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 4 ADET, ILARIS® SOLUCIÓN INYECTABLE 150 MG/ ML
  3. Drug

    Tolfenamic acid

    go.drugbank.com/drugs/DB09216
    Approved

    Tolfenamic acid, with the formula N-(2-methyl-3-chlorphenyl)-anthranilic acid, is a nonsteroidal anti-inflammatory agent. … [A31824] It was discovered by scientists at Medica Pharmaceutical Company in Finland. It is used in the UK as a treatment for migraine under the name of Clotam.

    Categories: Cytochrome P-450 Substrates, Non COX-2 selective NSAIDSProducts: TOLFEDINE TABLETS 6 MG, TOLFEDINE TABLET 60 MG
  4. Drug

    Polyethylene glycol

    go.drugbank.com/drugs/DB09287
    ApprovedInvestigationalVet approved

    PEGs have a long history of gastroenterology: PEG 3350 is a common over-the-counter osmotic laxative used to relieve occasional constipation. … Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.

    Mixtures: Gavilyte-N, Gavilyte G TmCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitors
  5. Drug

    Tozuleristide

    go.drugbank.com/drugs/DB15375
    Investigational

    Tozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery).

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingSynonyms: N6.27-(6-(2-(7-(1,1-DIMETHYL-3-(4-SULFONATOBUTYL)-1H-BENZO(E)INDOL-1-IUM-2-YL)HEPTA-2,4,6-TRIENYLIDENE)-1,1-DIMETHYL-1,2-DIHYDRO-3H-BENZO(E)INDOL-3-YL)HEXANOYL)(15-ARGININE(K>R),23-ARGININE(K>R))CHLOROTOXIN
  6. Drug

    Guaifenesin

    go.drugbank.com/drugs/DB00874
    ApprovedInvestigationalVet approved

    After the negotiation between FDA and major manufacturers, a voluntary transition of labels for not using guaifenesin in children under the age of 4 years was endorsed by FDA in 2008 [F4525]. … Regardless, on March 1, 2007, the FDA received a petition asking the FDA to notify the public that some antitussives, expectorants, decongestants, antihistamines, and cough/cold combinations are not known

    Mixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, BİCANA 1,5 MG/5 ML + 66,5 MG/5 ML ŞURUP, 100 MLInternational brands: Duratuss G
  7. Drug

    Perampanel

    go.drugbank.com/drugs/DB08883
    ApprovedInvestigational

    Perampanel is a noncompetitive AMPA glutamate receptor antagonist. … The FDA label includes an important black-boxed warning of serious or life-threatening behavioral and psychiatric reactions in patients taking Fycompa™.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one
  8. Drug

    Niclosamide

    go.drugbank.com/drugs/DB06803
    ApprovedInvestigationalVet approved

    Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases. … Over 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms. They are an even greater problem in domestic animals.

    Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesProducts: YOMESAN 500 MG TABLET, 4 ADET, TENYADÜŞ TABLET, 4 ADET
  9. Indication

    Stage 4 Follicular Lymphoma ( FL)

    go.drugbank.com/conditions/DBCOND0154147
    Drugs: Obinutuzumab
    Synonyms: Stage 4 Follicular Lymphoma ( FL)
  10. Drug

    3alpha,6beta,7beta,12alpha-tetrahydroxy-5beta-cholan-24-oic acid

    go.drugbank.com/drugs/DB18044
    Experimental

    Synonyms: 3a,6b,7b,12a-(OH)4-5b-cholanic acid, (3α,5β,6β,7β,12α)-3,6,7,12-Tetrahydroxycholan-24-oic acid