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Displaying results 3971 - 3980 of 10000 in total
  1. Drug

    Tirabrutinib

    go.drugbank.com/drugs/DB15227
    Investigational

    Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).

    Synonyms: 6-amino-9-[(3R)-1-but-2-ynoylpyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-oneCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Icalcaprant

    go.drugbank.com/drugs/DB21651
    Investigational

    Icalcaprant is a small molecule drug. The usage of the INN stem '-caprant' in the name indicates that Icalcaprant is a kappa-opioid receptor (KOR) antagonist. … Icalcaprant has a monoisotopic molecular weight of 406.2 Da.

    Synonyms: 4-(4-{[(2S)-2-(3-methoxy-1-methyl-1H-pyrazol-4-yl)pyrrolidin-1-yl]methyl}phenoxy)benzamide
  3. Drug

    Fisetin

    go.drugbank.com/drugs/DB07795
    Investigational

    Synonyms: 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one, 3,3',4',7-TetrahydroxyflavoneCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-Ring
  4. Drug

    Geraniol

    go.drugbank.com/drugs/DB14183
    Approved

    Sensitivity to geraniol may be identified with a clinical patch test. … Geraniol has demonstrated a wide spectrum of pharmacological activities including antimicrobial, anti-inflammatory, antioxidant, anti-cancer, and neuroprotective to name a few [A34260,A34261,A34262].

    Synonyms: 2-trans-3,7-Dimethyl-2,6-octadien-1-ol, (2E)-3,7-dimethylocta-2,6-dien-1-ol
  5. Drug

    Methysergide

    go.drugbank.com/drugs/DB00247
    ApprovedWithdrawn

    An ergot derivative that is a congener of lysergic acid diethylamide.

    Synonyms: 1-Methyl-dextro-lysergic acid (+)-1-hydroxy-2-butylamide, (+)-N-(1-(Hydroxymethyl)propyl)-1-methyl-D-lysergamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  6. Drug

    Tinlarebant

    go.drugbank.com/drugs/DB17832
    Investigational

    Synonyms: 1-(3-(4-(3,4-difluoro-2-(trifluoromethyl)phenyl)piperidine-1-carbonyl)-1h,4h,5h,6h,7h-pyrazolo(3,4-c)pyridin-6-yl)ethan-1-one, 1-(3-{4-[3,4-Difluoro-2-(Trifluoromethyl)Phenyl]Piperidine-1-Carbonyl}-1H,4H,5H,6H,7H-Pyrazolo[3,4-C]Pyridin-6-Yl)Ethan-1-One
  7. Drug

    Olenasufligene relduparvovec

    go.drugbank.com/drugs/DB16264
    Investigational

    It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.[L46671]

    Synonyms: Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying)
  8. Drug

    DF-1001

    go.drugbank.com/drugs/DB18231
    Investigational

    Synonyms: Heterodimeric multi-specific IgG1 antibody targeting human epidermal growth factor receptor 2 (HER2) and NKG2D on natural killer (NK) and cytotoxic T-cells
  9. Drug

    DMP-777

    go.drugbank.com/drugs/DB18488
    Experimental

    DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase.

    Synonyms: 1-AZETIDINECARBOXAMIDE, N-((1R)-1-(1,3-BENZODIOXOL-5-YL)BUTYL)-3,3-DIETHYL-2-(4-((4-METHYL-1-PIPERAZINYL)CARBONYL)PHENOXY)-4-OXO-, (2S)-Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Tomaralimab

    go.drugbank.com/drugs/DB15415
    Investigational

    Tomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).

    Synonyms: Humanized IGG4 monoclonal antibody against toll-like receptor 2 for prevention of ischemia/reperfusion tissue injuryCategories: Immunoglobulin G