Search
Beta-galactosidase
go.drugbank.com/bio_entities/BE0009999TargetEnzymeHumansCleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans
Synonyms: Elastin receptor 1C-type lectin domain family 14 member A
go.drugbank.com/bio_entities/BE0005467TargetHumansSynonyms: Epidermal growth factor receptor 5Cyclic GMP
go.drugbank.com/drugs/DB02315ExperimentalIt is a cellular regulatory agent and has been described as a second messenger. … Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
Categories: Heterocyclic Compounds, 2-RingSynonyms: 3',5'-cyclic GMP, Guanosine 3',5'-cyclic phosphateAT-301
go.drugbank.com/drugs/DB16507InvestigationalAT-301 was under investigation in clinical trial NCT01675284 to evaluate the safety, reactogenicity, and humoral immune responses to an inactivated H5N1 influenza vaccine
NXN-188
go.drugbank.com/drugs/DB06096InvestigationalNXN-188 is a first-in-class, dual-action small molecule incorporating both neuronal nitric oxide synthase (nNOS) inhibition and 5-HT agonism that is being developed for the treatment of acute migraine.
Repinotan
go.drugbank.com/drugs/DB06506InvestigationalRepinotan is a high-affinity, selective, full agonist of the 5HT1A-receptor subtype with neuroprotective properties.
Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT1A Receptor AntagonistsOsemozotan
go.drugbank.com/drugs/DB05339ExperimentalMN-305 is a novel, potent and highly selective serotonin 5-HT1A receptor agonist under development by MediciNova for the treatment of anxiety disorders beginning with Generalized Anxiety Disorder (GAD)
Categories: Heterocyclic Compounds, 1-RingOSI-461
go.drugbank.com/drugs/DB05415InvestigationalOSI-461 is a second-generation molecule belonging to a new class of drugs termed selective apoptotic anti-neoplastic drugs (SAANDs).
Mavoglurant
go.drugbank.com/drugs/DB13004InvestigationalMavoglurant has been used in trials studying the treatment of Patient Diagnosed With OCD and and Resistant to SSRI Treatment (Failed SSRI Over 12 Weeks at Appropriate Doses).
Categories: Heterocyclic Compounds, 2-Ring