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TOP-1288
go.drugbank.com/drugs/DB14839InvestigationalTOP-1288 is under investigation in clinical trial NCT02888379 (Phase 2a Study to Evaluate the Safety/Tolerability and Efficacy of TOP1288 200 mg Rectal Solution Once Daily for 4 Weeks in Ulcerative Colitis
Folic acid
go.drugbank.com/drugs/DB00158ApprovedInvestigationalNutraceuticalVet approvedAs humans are unable to synthesize folic acid endogenously, diet and supplementation is necessary to prevent deficiencies. … Folic acid is typically supplemented during pregnancy to prevent the development of NTDs and in individuals with alcoholism to prevent the development of neurological disorders, for example.
Synonyms: Folic acid, Folic-acidMixtures: Sodium polysulthionate and folic acid, Sodium Polysulthionate and Folic AcidVayarin
go.drugbank.com/drugs/DB09328ApprovedVayarin contains _Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. … Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure [L1502].
Synonyms: Phosphatidylserine, DHA, and EPABoric acid
go.drugbank.com/drugs/DB11326ApprovedInvestigationalIt is known to exhibit some antibacterial activity against infections such as bacterial vaginosis and candidiasis [A32449]. … Boric acid is typically utilized in industrial processing and manufacturing, but is also used as an additive in pharmaceutical products, cosmetics, lotions, soaps, mouthwash, toothpaste, astringents, and
Synonyms: Boric acid, boracic acidMixtures: OP IZEUndecylenic acid
go.drugbank.com/drugs/DB11117ApprovedDue to its bifunctional properties, undecylenate is also used as a linking molecule to conjugate other biomolecules such as proteins. It serves as an acid moiety for anabolic steroid boldenone. … Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat.
Synonyms: Undecenoic acid, 10-undecenoic acidMixtures: Fungi Nail Toe and Foot MS, Fungi Nail Toe and Foot MSFusidic acid
go.drugbank.com/drugs/DB02703ApprovedInvestigationalIt is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections. … An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis.
Synonyms: Fucidin acid, Fusidic acidSalts: Fusidic acid hemihydrateAcetylsalicylic acid
go.drugbank.com/drugs/DB00945ApprovedInvestigationalVet approvedAlso known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. … Acetylsalicylic acid has both anti-inflammatory and antipyretic effects.
Synonyms: 2-Acetoxybenzoic acid, acetyl salicylic acidInternational brands: Solprin acidSalicylic acid
go.drugbank.com/drugs/DB00936ApprovedInvestigationalVet approvedA compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions.
Synonyms: Salicylic acid, 2-Hydroxybenzoic acidMixtures: Dermaharmony Sulfur and Salicylic Acid, Dermaharmony Sulfur and Salicylic AcidTranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigationalIt possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent. … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding.
Categories: Amino Acids, Peptides, and Proteins, Blood and Blood Forming OrgansSynonyms: Tranexmic acid, Tranexamic acid