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Displaying results 31 - 40 of 10000 in total
  1. Drug

    AVR-RD-04

    go.drugbank.com/drugs/DB18644
    Experimental

    It consists of autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin. … AVR-RD-04 is an investigational gene therapy for cystinosis.

    Synonyms: autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin
  2. Drug

    Idursulfase beta

    go.drugbank.com/drugs/DB16190
    Investigational

    Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).

    Synonyms: Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform beta)
  3. Drug

    Exebacase

    go.drugbank.com/drugs/DB16161
    Investigational

    Exebacase is under investigation in clinical trial NCT03163446 (Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia).

    Synonyms: Des-met1-putative phage lysin (streptococcus phage phi891591), produced in escherichia coli
  4. Drug

    TVI-Brain-1

    go.drugbank.com/drugs/DB17227
    Investigational

    Synonyms: Attenuated autologous cancer cells and granulocyte macrophage colony stimulating factor in combination with activated autologous blood derived T-cells
  5. Drug

    Tea tree oil

    go.drugbank.com/drugs/DB11218
    ApprovedNutraceutical

    It has been a popular ingredient in a variety of household and cosmetic products due to its antiseptic, anti-inflammatory, broad-spectrum antimicrobial and antioxidant properties [A32438]. … It may be referred to as _Melaleuca alternifolia_ oil.

    Mixtures: I Dew Care Tea Tree O StarterkitSynonyms: Snow-in-summer leaf oil
  6. Drug

    Eltrapuldencel-T

    go.drugbank.com/drugs/DB17329
    Investigational

    Synonyms: Autologous dendritic cells loaded with antigen from self-renewing, proliferating autologous irradiated tumour cells, in a solution of granulocyte-macrophage colony stimulating factor (GM-CSF)
  7. Drug

    Padnarsertib

    go.drugbank.com/drugs/DB19243
    Investigational

    Synonyms: Pak4-in-1, 2-propenamide, 3-(6-amino-3-pyridinyl)-n-((5-(4-((4,4-difluoro-1-piperidinyl)carbonyl)phenyl)-7-(4-fluorophenyl)-2-benzofuranyl)methyl)-, (2e)-
  8. Drug

    IFx-Hu2.0

    go.drugbank.com/drugs/DB18396
    Investigational

    IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.

    Synonyms: Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic, streptococcal Emm55 protein, complexed with in vivo-jetPEI® polymer-based reagent linear
  9. Drug

    scAAV9.U7.ACCA

    go.drugbank.com/drugs/DB18582
    Investigational

    scAAV9.U7.ACCA is a non-replicating recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding … Developed by Nationwide Children’s Hospital, it is being investigated for the treatment of Duchenne muscular dystrophy.

    Synonyms: non-replicating recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding RNA
  10. Drug

    ODM-207

    go.drugbank.com/drugs/DB18820
    Investigational

    Synonyms: BET-IN-4