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Displaying results 31 - 40 of 3732 in total
  1. Drug

    Nipocalimab

    go.drugbank.com/drugs/DB16257
    ApprovedInvestigational

    Nipocalimab-aahu is a neonatal Fc receptor (FcRn) blocker used to treat certain antibody-mediated autoimmune diseases.

    Synonyms: immunoglobulin G1-lambda, anti-[Homo sapiens FCGRT (Fc fragment of IgG receptor and transporter, neonatal Fc receptor, FcRn, transmembrane alpha chain of the neonatal receptor)], Homo sapiens monoclonal, Immunoglobulin g1, anti-(human neonatal fc receptor) (human monoclonal m281 .gamma.-1 chain), disulfide with human monoclonal m281 .lambda.-chain, dimerCategories: Neonatal Fc Receptor Blocker
  2. Drug

    Arbutin

    go.drugbank.com/drugs/DB11217
    Approved

    It is found in foods, over-the-counter drugs, and herbal dietary supplements [F43].

    Mixtures: The Prestige BB SPF25 PA 2Plus, Absolute Total BB SPF37 PA 3PlusSynonyms: p-hydroxyphenyl β-D-glucoside, p-hydroxyphenyl β-D-glucopyranoside
  3. Drug

    Satralizumab

    go.drugbank.com/drugs/DB15762
    ApprovedInvestigational

    satralizumab formulation developed by Chugai Pharmaceutical and Roche,[L15536] is uniquely formulated with "recycling antibody technology" whereby the association of satralizumab to IL-6 receptors occurs in a pH-dependent … manner[A218551] - this allows satralizumab to bind an IL-6 receptor until it reaches an endosome, after which the drug may dissociate from the receptor and move back into the plasma to act again.

    Synonyms: Humanised anti-IL-6 receptor monoclonal antibodyCategories: Interleukin-6 Receptor Antagonist
  4. Drug

    Chloroxylenol

    go.drugbank.com/drugs/DB11121
    Approved

    Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. ...

    Synonyms: p-chloro-m-xylenol, p-chloro-3,5-xylenolProducts: Tork Foam Antibacterial, Tork Advanced Antimicrobial
  5. Drug

    Dolutegravir

    go.drugbank.com/drugs/DB08930
    ApprovedInvestigational

    Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent to...

    Mixtures: Triumeq PDCategories: P-glycoprotein substrates
  6. Drug

    Nifedipine

    go.drugbank.com/drugs/DB01115
    ApprovedInvestigational

    Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972....

    Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: Adalat Pa 20, Apo-nifed Pa
  7. Drug

    Tagraxofusp

    go.drugbank.com/drugs/DB14731
    ApprovedInvestigational

    Tagraxofusp is a CD123-directed cytotoxin. It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in Escherichia co...

    Synonyms: Diphtheria toxin-il-3 fusion protein targeting IL-3 receptor
  8. Drug

    Methyl aminolevulinate

    go.drugbank.com/drugs/DB00992
    ApprovedInvestigational

    Methyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.

    Products: KRX Aesthetics PD-13 Therapy
  9. Drug

    Amsacrine

    go.drugbank.com/drugs/DB00276
    ApprovedInvestigationalWithdrawn

    Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in c...

    International brands: AMSA P-DCategories: P-glycoprotein inhibitors
  10. Drug

    Insulin human

    go.drugbank.com/drugs/DB00030
    ApprovedInvestigational

    Due to the added crystals, NPH insulin is typically cloudy when compared to other forms of insulin and has a neutral pH. … Unfortunately, limited uptake by physicians and patients, poor sales, bulky packaging, and concerns over the possible impact on lung cancer development resulted in Exubera products being withdrawn from

    Mixtures: HUMINSULIN PROFIL III F PE, HUMINSULIN PROFIL III F PECategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme Inducers