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Olanzapine
go.drugbank.com/drugs/DB00334ApprovedInvestigational[A177011] Olanzapine was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996.[T548] … [A176996] Its chemical structure contains a thieno[2,3-b][1,5]benzodiazepine core, and has a methyl group attached to the piperazine ring.
Mixtures: TARGET 12MG /25 MG KAPSUL, 90 ADET, TARGET 12MG /50 MG KAPSUL, 90 ADETProducts: OLANZAPIN GLENMARK EU 10MG, OLANZAPIN - CT 10MG TABLFurosemide
go.drugbank.com/drugs/DB00695ApprovedInvestigationalVet approvedIt is an anthranilic acid derivative. … Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients.
Mixtures: SPIRO COMP RATIO 50MG/20MG, SPIRO COMP RATIO 50MG/20MGCategories: Increased Diuresis at Loop of HenleOlmesartan
go.drugbank.com/drugs/DB00275ApprovedInvestigational[A175330] It was developed by Daiichi Sankyo Pharmaceuticals and approved in 2002.[A175345, L12882] … The angiotensin II receptor blocker (ARB) family of drugs unique in that it blocks all angiotensin II activity, regardless of where or how it was synthesized.
Mixtures: VOCADO 40MG/10MG, VOCADO 40MG/10MGProducts: VOTUM 10MG, OLMETEC 10MGLisinopril
go.drugbank.com/drugs/DB00722ApprovedInvestigational[A184853] It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system. … [A184844] Lisinopril was granted FDA approval on 29 December 1987.[L8384]
Mixtures: Lisinopril-HCT G.L. 20mg/25mg - Tabletten, LISIPLUS AL 10MG/12.5MGProducts: LISINOPRIL - CT 20MG TABL, Lisinopril 10mgEstradiol valerate
go.drugbank.com/drugs/DB13956ApprovedInvestigationalVet approvedFirst-pass metabolism by the gut and the liver quickly degrades the estradiol molecule before it gets a chance to enter systemic circulation and exert its estrogenic effects [A12102]. … As a pro-drug of estradiol, estradiol acetate therefore has the same downstream effects within the body through binding to the Estrogen Receptor (ER) including ERα and ERβ subtypes, which are located in
Mixtures: ARIORA 1MG/2MG, ARIORA 1MG/2MGProducts: PMS-estradiol Valerate Inj 10mg/ml, Delestrogen Inj 10mg/mlTemozolomide
go.drugbank.com/drugs/DB00853ApprovedInvestigational[L32033] Temozolomide was granted FDA approval on August 11, 1999, as an oral capsule and subsequently on February 27, 2009, as an intravenous injection. … It is currently marketed under the trademark TEMODAR® by Merck.[L32033]
Synonyms: 3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamideProducts: TEMODAL 180MG, TEMODAL 180MG HKP IN BTLCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigational[A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors. … [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230]
Products: CITALOPRAM HEUMA 10MG NET, CITALOPRAM - CT 20MGThioridazine
go.drugbank.com/drugs/DB00679ApprovedWithdrawnIt has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p618). Thioridazine was withdrawn worldwide in 2005 due to its association with cardiac arrythmias.
Products: PMS-thioridazine 10mg/tab USP, Novo-ridazine 10mgGalantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigationalIt also acts as an allosteric modulator of the nicotinic receptor, giving its dual mechanism of action clinical significance. … [L13571] It is therefore not considered to be a disease-modifying drug.
Mixtures: GALNORA 8MG + 16MG HKP RET, GALNORA 8MG + 16MG HKP RETProducts: PMS-galantamine ER, GALANTAMIN RATIO 16MG RETLeflunomide
go.drugbank.com/drugs/DB01097ApprovedInvestigationalLeflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Products: LEFLUNOMID HEU 10MG NET, LEFLUNOMID HEU 20MG NET