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Empagliflozin
go.drugbank.com/drugs/DB09038ApprovedInvestigationalEmpagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney. It is used clinically as an adjunct to diet and exercise, often in combinatio...
Categories: metformin and empagliflozin, metformin, linagliptin and empagliflozinGlipizide
go.drugbank.com/drugs/DB01067ApprovedInvestigationalAccording to the 2018 Clinical Practice Guidelines by Diabetes Canada, sulfonylurea drugs are considered a second-line glucose-lowering therapy following metformin. … [A179485] Glipizide was first approved by the FDA in 1994 and is available in extended-release tablets under the brand name Glucotrol®, as well as in combination with metformin under the brand name Metaglip
Mixtures: Glipizide and Metformin Hydrochloride, Glipizide and Metformin HydrochloridePR-15
go.drugbank.com/drugs/DB06037InvestigationalPR-15 is a novel anti-platelet protein with the potential to treat arterial thrombosis occurring during acute coronary syndromes without the bleeding risk associated with existing agents.
Synonyms: RevaceptDapagliflozin
go.drugbank.com/drugs/DB06292ApprovedInvestigationalDapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin help...
Mixtures: Apo-dapagliflozin-metformin, Apo-dapagliflozin-metforminCategories: metformin and dapagliflozin, metformin, saxagliptin and dapagliflozinEpidermal Growth Factor Receptor variant III (EGFRvIII) chimeric antigen receptor T cells
go.drugbank.com/drugs/DB18654InvestigationalSynonyms: Epidermal Growth Factor Receptor variant III (EGFRvIII) chimeric antigen receptor T cells, Autologous Chimeric Antigen Receptor (CAR) Modified Recombinant T Cells Targeting EGFRvIIILB54640
go.drugbank.com/drugs/DB18331InvestigationalLB54640 is orally-administered small molecule agonist of the melanocortin 4 receptor.
Synonyms: Oral melanocortin 4 receptor agonist, Small molecule melanocortin 4 receptor agonistDextromethorphan
go.drugbank.com/drugs/DB00514ApprovedInvestigationalDextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethor...
Mixtures: K.B. FEDAMOLCategories: NMDA Receptor Antagonists, Sigma-1 Receptor AgonistsSpesolimab
go.drugbank.com/drugs/DB15626ApprovedInvestigationalSpesolimab is an interleukin-36 (IL-36) receptor antagonist.
Categories: Interleukin-36 Receptor AntagonistSynonyms: Immunoglobulin G1, anti-(human interleukin 36 receptor) (humanized monoclonal BI 655130 gamma1-chain), disulfide with humanized monoclonal BI 655130 kappa-chain, dimerTeprotumumab
go.drugbank.com/drugs/DB06343ApprovedInvestigationalTeprotumumab is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor.
Categories: Insulin-like Growth Factor-1 Receptor InhibitorSynonyms: Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human monoclonal heavy chain), disulfide with human monoclonal light chain, dimerSaxagliptin
go.drugbank.com/drugs/DB06335ApprovedInvestigationalSaxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Mixtures: Saxagliptin and Metformin, Saxagliptin and MetforminCategories: metformin and saxagliptin, metformin, saxagliptin and dapagliflozin