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Displaying results 391 - 400 of 10000 in total
  1. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0001210
    Target

    Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. … Gag-Pol polyprotein Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol
  2. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0001594
    TargetHuman immunodeficiency virus type 1 group M subtype B (isolate HXB2)

    Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. … Gag-Pol polyprotein Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol
  3. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0002050
    TargetHuman immunodeficiency virus type 1 group M subtype B (isolate HXB2)

    Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. … Gag-Pol polyprotein Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol
  4. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0003804
    Target

    Gag-Pol polyprotein and Gag polyprotein may regulate their own translation, by the binding genomic RNA in the 5'-UTR. … At low concentration, Gag-Pol and Gag would promote translation, whereas at high concentration, the polyproteins encapsidate genomic RNA and then shut off translation (By similarity).

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol
  5. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0003967
    TargetMoMLV

    During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag-Pol, or to Gag-Pol binding host factors. … Gag-Pol polyprotein Plays a role in budding and is processed by the viral protease during virion maturation outside the cell.

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr180gag-pol
  6. Drug

    Benserazide

    go.drugbank.com/drugs/DB12783
    ApprovedInvestigational

    When levodopa is used by itself as a therapy for treating Parkinson's disease, its ubiquitous metabolism into dopamine is responsible for a resultant increase in the levels of circulating dopamine in the … Moreover, the European Medcines Agency has conferred an orphan designation upon benseraside since 2015 for its potential to be used as a therapy for beta thalassaemia as well [F3].

    Mixtures: MADOPAR ROCHE 125 CAPSULE, MADOPAR ROCHE TABLET 250MGCategories: Aromatic L-amino Acid Decarboxylase Inhibitors
  7. Drug

    Naproxen

    go.drugbank.com/drugs/DB00788
    ApprovedInvestigationalVet approved

    Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. … [A179098] Given its overall tolerability and effectiveness, naproxen can be considered a first line treatment for a variety of clinical situations requiring analgesia.

    Mixtures: ORTOFLEX ® L, ALLI_VIAX-PROCategories: Topical Products for Joint and Muscular Pain, Antiinflammatory Products for Vaginal Administration
  8. Drug

    Cefuroxime

    go.drugbank.com/drugs/DB01112
    ApprovedInvestigational

    It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: CEFUROXIM AL 250, CEFUROXIM AL 500
  9. Drug

    Topiramate

    go.drugbank.com/drugs/DB00273
    ApprovedInvestigational

    [L10550] Characteristics that distinguish topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen. … In 2004, topiramate was approved for the prevention of migraine in adults.

    Products: Pro-topiramate, TOPIRAMAT AL 25MG
  10. Drug

    Isopropyl alcohol

    go.drugbank.com/drugs/DB02325
    ApprovedInvestigational

    It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.

    Mixtures: ST COVID-POD (Saliva Collection Kit), Pro GuardCategories: Compounds used in a research, industrial, or household setting