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Larotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigationalLarotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important role in tumor cell gr...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: VITRAKVI®CÁPSULAS DE 100MGPotassium nitrate
go.drugbank.com/drugs/DB11090ApprovedInvestigationalPotassium nitrate is an inorganic salt with a chemical formula of KNO3. It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, r...
Mixtures: Opalescence PF, The DuoProducts: Dr. Sheffield Sensitive CareBosutinib
go.drugbank.com/drugs/DB06616ApprovedInvestigationalPhiladelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein. … -alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: BOSUTINIB DR. REDDY?SHydroxyprogesterone caproate
go.drugbank.com/drugs/DB06789ApprovedHydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyproge...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InducersSynonyms: Caproato de hidroxiprogesteronaRabeprazole
go.drugbank.com/drugs/DB01129ApprovedInvestigationalRabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersProducts: Rabeprazole Sodium DR, Raberprazole Sodium D/rChloral hydrate
go.drugbank.com/drugs/DB01563ApprovedIllicitInvestigationalVet approvedA hypnotic and sedative used in the treatment of insomnia. The safety margin is too narrow for chloral hydrate to be used as a general anesthetic in humans, but it is commonly used for that purpose in animal experiments. It is no longer ...
Products: HIDRATO DE CLORAL 10%SOLUCION ORAL(GOTAS)Levmetamfetamine
go.drugbank.com/drugs/DB09571ApprovedLevomethamphetamine, the L-enantiomer of methamphetamine is a sympathomimetic vasoconstrictor used in some over-the-counter (OTC) nasal decongestant inhalers in the United States.
Products: Vapor Inhaler levmetamfetamine nasal decongestant, DG healthRisperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigationalRisperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain. … [L12885] Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways
Categories: Dopamine D2 Receptor Antagonists, P-glycoprotein substratesProducts: RISPERDAL CONSTA FOR INJECTION 25 mg/vial, RISPERDAL CONSTA FOR INJECTION 37.5 mg/vialMethocarbamol
go.drugbank.com/drugs/DB00423ApprovedInvestigationalVet approvedMethocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain. It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the ...
Products: Methocarbamol Granules DC 90%, Methocarbomal Granules DC 90%Darifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalDarifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. This block reduces the urgency to urinate and so it...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: ENABLEX ® 15 MG TABLETAS DE LIBERACION PROLONGADA, ENABLEX ® 7.5 MG TABLETAS DE LIBERACION PROLONGADA