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Displaying results 4001 - 4010 of 7063 in total
  1. Drug

    Tenecteplase

    go.drugbank.com/drugs/DB00031
    ApprovedInvestigational

    Tenecteplase is a tissue plasminogen activator (tPA) developed from modifications of natural human tPA complementary DNA (cDNA). … It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine 117 with glutamine within the kringle 1 domain, and a tetra-alanine substitution at amino acids

  2. Drug

    BNT162B2 Omicron (LP.8.1)

    go.drugbank.com/drugs/DB23337
    Approved

    [L53723] The 2025-2026 formulation of Pfizer-BioNTech's Comirnaty was approved by the US FDA in August 2025.[L53728]

  3. Drug

    Gemeprost

    go.drugbank.com/drugs/DB08964
    ApprovedWithdrawn

    It is not FDA-approved but available in Japan marketed as Preglandin. … Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion.

  4. Drug

    Arimoclomol

    go.drugbank.com/drugs/DB05025
    Approved

    Arimoclomol is a hydroxylamine derivative [A264414] and a heat-shock protein-70 (HSP70) co-inducer. … [L51384] Arimoclomol was approved by the FDA on September 20, 2024, making it the first treatment for Niemann-Pick disease, type C (NPC).

  5. Drug

    Aliskiren

    go.drugbank.com/drugs/DB09026
    ApprovedInvestigational

    [A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007.

  6. Drug

    Tozasertib

    go.drugbank.com/drugs/DB19675
    Investigational

    Tozasertib has a monoisotopic molecular weight of 464.21 Da. … Tozasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Tozasertib is a serine/threonine kinase inhibitor.

  7. Drug

    Conteltinib

    go.drugbank.com/drugs/DB21262
    Investigational

    Conteltinib has a monoisotopic molecular weight of 635.34 Da. … Conteltinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Conteltinib is a tyrosine kinase inhibitor.

  8. Drug

    Osunprotafib

    go.drugbank.com/drugs/DB21547
    Investigational

    Osunprotafib has a monoisotopic molecular weight of 385.15 Da. … Osunprotafib is a small molecule drug. The usage of the INN stem '-protafib' in the name indicates that Osunprotafib is a human protein tyrosine phosphatase (HPTP) inhibitor.

  9. Drug

    Zelicapavir

    go.drugbank.com/drugs/DB21662
    Investigational

    Zelicapavir has a monoisotopic molecular weight of 549.17 Da. … Zelicapavir is a small molecule drug. The usage of the INN stem '-capavir' in the name indicates that Zelicapavir is a viral capsid and nucleocapsid inhibitor.

  10. Drug

    Zoracopan

    go.drugbank.com/drugs/DB21702
    Investigational

    Zoracopan has a monoisotopic molecular weight of 614.16 Da. … Zoracopan is a small molecule drug. The usage of the INN stem '-copan' in the name indicates that Zoracopan is a complement receptor antagonist/complement inhibitor.