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Displaying results 4011 - 4020 of 10000 in total
  1. Drug

    Bardoxolone

    go.drugbank.com/drugs/DB12651
    Investigational

    It is a synthetic triterpenoid and a highly potent activator of redox-sensitive signaling pathways that induce programmed cell death (apoptosis) in cancer cells that are under high levels of intrinsic … In contrast, Bardoxolone in normal cells induces protective antioxidant/anti-inflammatory responses.

  2. Drug

    Clopenthixol

    go.drugbank.com/drugs/DB13841
    Investigational

    It is an antagonist at D1 and D2 dopamine receptors.

  3. Drug

    Docosanol

    go.drugbank.com/drugs/DB00632
    Approved

    Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). A saturated 22-carbon aliphatic alcohol, docosanol exhibits antiviral activity against many lipid e...

    Synonyms: N-DocosanolProducts: Erazaban 100 mg/g Creme
  4. Drug

    Girentuximab I-124

    go.drugbank.com/drugs/DB15025
    Investigational

    Girentuximab I-124 is under investigation in clinical trial NCT01762592 (REDECT 2: REnal Masses: Pivotal Trial to DEteCT Clear Cell Renal Cell Carcinoma With PET/CT).

  5. Drug

    Mirfentanil

    go.drugbank.com/drugs/DB09175
    Experimental

    At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in morphine-treated monkeys; however, it also reverses naloxone-precipitated withdrawal in pigeons trained … At high doses, it exhibits analgesic activity which is not fully reversed by opioid antagonists, suggesting that the drug has both opioid and non-opioid mechanisms of action.

  6. Drug

    Levosalbutamol

    go.drugbank.com/drugs/DB13139
    Approved

    [Salbutamol] has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. … Levosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

    Products: LEVACORT RESPULAS 1.25 MG/2.5 ML, LEVODOSE 100 MG INHALASYON ICIN TOZ ICEREN BLISTER, 60 DOZ
  7. Drug

    Sincalide

    go.drugbank.com/drugs/DB09142
    Approved

    It is identified as the 8-amino acid C-terminal segment of cholecystokinin and is also known as _CCK-8_. … Sincalide is a medication given by injection to assist in the diagnosis of gallbladder and pancreas disorders.

  8. Drug

    Oxyphenisatin

    go.drugbank.com/drugs/DB04823
    ApprovedWithdrawn

    It may cause jaundice.

  9. Drug

    Liposomal prostaglandin E1

    go.drugbank.com/drugs/DB05391
    Investigational

    Liposome-encapsulated form of prostaglandin E1 (Liprostin) is known to be a potent vasodilator and platelet inhibitor as well as an anti-inflammatory and anti-thrombotic agent. … The liposomal formulation of PGE-1 changes the drug’s dynamics and improve its therapeutic index in ways that PGE-1 alone could not achieve.

    Synonyms: Liposomal prostaglandin E1
  10. Drug

    Nitrofural

    go.drugbank.com/drugs/DB00336
    ApprovedVet approvedWithdrawn

    It is used for superficial wounds, burns, ulcers, and skin infections. Nitrofural has also been administered orally in the treatment of trypanosomiasis.