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Riluzole
go.drugbank.com/drugs/DB00740ApprovedInvestigationalA glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesProducts: TEGLUTIK® SUSPENSIÓN ORAL 5 MG/ML, Teglutik 5 mg/ml Suspension zum EinnehmenAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigational(NMDA) receptor,[A18263] indicating a role for the glutamatergic system in the pathophysiology of ADHD. … More recently, positron emission tomography (PET) imaging studies in rhesus monkeys have shown that atomoxetine also binds to the serotonin transporter (SERT),[A178111] and blocks the N-methyl-d-aspartate
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: STRATTERA 4 MG/ML ORAL ÇÖZELTI, ATTEX 4 MG/ML ORAL ÇÖZELTİ, 100 MLInterleukin-6
go.drugbank.com/bio_entities/BE0000918TargetHumansCytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Pr...
Polypeptides: Interleukin-6Synonyms: IL-6Kallikrein-6
go.drugbank.com/bio_entities/BE0001586TargetHumansSerine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular ma...
Polypeptides: Kallikrein-6Peroxiredoxin-6
go.drugbank.com/bio_entities/BE0004641TargetHumansThiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (PubMed:10893423, PubMed:9497358). Can reduce H(2)O(2) and short chain organic, fatty acid, and ph...
Polypeptides: Peroxiredoxin-6Cadherin-6
go.drugbank.com/bio_entities/BE0013474TargetHumansCadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types
Polypeptides: Cadherin-6Cefprozil
go.drugbank.com/drugs/DB01150ApprovedInvestigationalCefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Categories: Heterocyclic Compounds, 2-RingProducts: CEFPROZIL ORCHID EUROPE, PREFIX 125 MG/5 ML ORAL SÜSPANSIYON HAZIRLAMAK IÇIN TOZ, 60 MLCarbocisteine
go.drugbank.com/drugs/DB04339ApprovedInvestigational[A230993] Carbocisteine is currently not FDA or Health Canada approved, but is approved for use in Asia, Europe, and South America. … Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus.
Synonyms: (L)-2-Amino-3-(carboxymethylthio)propionic acid, (R)-S-(carboxymethyl)cysteineMixtures: TUSSYL® MIEL JARABE, AXIM TOSTHERAPY FORTE®Fludeoxyglucose (18F)
go.drugbank.com/drugs/DB09502ApprovedInvestigationalFludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with
Synonyms: Fluorine-18 2-Fluoro-2-deoxy-D-Glucose, 18-F FDGCategories: Compounds used in a research, industrial, or household settingClotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedThis drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s [A174094]. … As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094].
Mixtures: Imazol duo 10 mg/g + 2,5 mg/g Creme, KADEFUNGIN 6Categories: P-glycoprotein inducers, P-glycoprotein inhibitors