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R450

R450 is an alpha 1 antagonist that acts to tighten the muscle tone in the bladder. It is being considered for treatment of stress-related urinary incontinence.

Sepiapterin

[L53548,L53593] Sepiapterin was granted marketing authorization by the European Commission in June 2025 and by the US FDA in July 2025 for the treatment of adults and children with phenylketonuria. … Sepiapterin is a small molecule activator of phenylalanine hydroxylase (PAH) used to reduce phenyalanine levels in patients with phenylketonuria.

Guanosine tetraphosphate

This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis. … Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position.

Saccharin

Saccharin has been investigated for the treatment of Hypertension and Hyperglycemia.

Koeleria macrantha pollen

Koeleria macrantha pollen is mainly used in allergenic testing.

Lolium perenne subsp. multiflorum pollen

Lolium perenne subsp. multiflorum pollen is mainly used in allergenic testing.

Desoxyribonuclease

Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. … The enzyme's cofactor is reported to be magnesium (or manganese) ions, although the optimal concentration of the ion is independent of the enzyme concentration [A31251].

Cilansetron

Cilansetron is a 5HT-3 antagonist made by Solvay Pharmaceuticals that is currently under trial phase in the EU and US.

Dipyridamole

A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 199...

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