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Mecbotamab vedotin
go.drugbank.com/drugs/DB17442InvestigationalMecbotamab vedotin is an anti-Axl humanized monoclonal antibody conjugated to monomethyl auristatin E using a cleavable linker (CAB-Axl-ADC).[A255212]
Synonyms: -CHAIN, DIMER, THIOETHER WITH N-(((4-((N-(6-(3-MERCAPTO-2,5-DIOXO, IMMUNOGLOBULIN G1 (DE-450-LYSINE), ANTI-(HUMAN TYROSINE KINASE RECEPTOR AXL) (HUMAN-MUS MUSCULUS MONOCLONAL BA301 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL BA301 .KAPPA.Isoleucine
go.drugbank.com/drugs/DB00167ApprovedInvestigationalNutraceuticalAn essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of leucine. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.
Mixtures: NUTRIPLUS LIPID SENZA ELETTROLITI, NUTRIPLUS LIPID SENZA ELETTROLITISynonyms: 2-Amino-3-methylvaleric acid, α-amino-β-methylvaleric acidCobimetinib
go.drugbank.com/drugs/DB05239ApprovedInvestigationalCobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction … It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or metastatic BRAF V600 mutation-positive melanoma.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: COTELLIC® (COBIMETINIB) 20 MG TABLETAS RECUBIERTASLysine
go.drugbank.com/drugs/DB00123ApprovedInvestigationalNutraceuticalLysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. … Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it.
Mixtures: NUTRIPLUS LIPID SENZA ELETTROLITI, NUTRIPLUS LIPID SENZA ELETTROLITISynonyms: (S)-α,ε-diaminocaproic acid, 6-ammonio-L-norleucinePsychophysiological Disorders
go.drugbank.com/conditions/DBCOND0172355Drugs: MelperoneSynonyms: Psychosomatic factor in physical condition, NOS, Psychosomatic factor in physical condition (finding)NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
go.drugbank.com/bio_entities/BE0000093TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: CI-13kD-A, Complex I-13kD-AProtein RecA
go.drugbank.com/bio_entities/BE0001269TargetMycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded
Synonyms: Recombinase ACardiolipin Biosynthesis CL(a-13:0/18:2(9Z,11Z)/a-13:0/a-21:0)
smpdb.ca/view/SMP0043344DiseaseLast, cardiolipin synthase catalyzes the synthesis of cardiolipin by transferring a phosphatidyl group from a second CDP-diacylglycerol to PG. It requires a divalent metal cation cofactor. … All membrane-localized enzymes are coloured dark green in the image.
Cardiolipin Biosynthesis CL(a-13:0/18:2(9Z,11Z)/a-13:0/a-25:0)
smpdb.ca/view/SMP0043345DiseaseLast, cardiolipin synthase catalyzes the synthesis of cardiolipin by transferring a phosphatidyl group from a second CDP-diacylglycerol to PG. It requires a divalent metal cation cofactor. … All membrane-localized enzymes are coloured dark green in the image.
Cardiolipin Biosynthesis CL(a-13:0/18:2(9Z,11Z)/a-15:0/a-17:0)
smpdb.ca/view/SMP0043361DiseaseLast, cardiolipin synthase catalyzes the synthesis of cardiolipin by transferring a phosphatidyl group from a second CDP-diacylglycerol to PG. It requires a divalent metal cation cofactor. … All membrane-localized enzymes are coloured dark green in the image.