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Naldemedine
go.drugbank.com/drugs/DB11691ApprovedInvestigationalIt is a modified form of [DB00704] to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier. … Naldemedine was approved in 2017 in both the US and Japan for the treatment of Opioid-induced Constipation.
Lasalocid
go.drugbank.com/drugs/DB11423ExperimentalVet approvedLasalocid is an agent that presents antibacterial and coccidiostat activities. It is produced by strains of _Streptomyces lasaliensis_.
Categories: Compounds used in a research, industrial, or household settingCorticorelin
go.drugbank.com/drugs/DB05394InvestigationalCorticotropin-releasing factor is studied in the treatment of brain cancer. It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory. … It is a type of neurohormone, also called hCRF.
Flortaucipir
go.drugbank.com/drugs/DB15033InvestigationalFlortaucipir is under investigation in clinical trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol).
Categories: Compounds used in a research, industrial, or household settingUlaritide
go.drugbank.com/drugs/DB05034InvestigationalUlaritide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. … Ularitide is currently in Phase 2 development as a potential treatment for patients with acute decompensated heart failure (ADHF).
Tabelecleucel
go.drugbank.com/drugs/DB17072ApprovedInvestigational[A253292,A253297,L43557] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended tabelecleucel be granted marketing authorization for the treatment of adult and … It is produced by mixing T-cells with B-cells that have been infected with the Epstein-Barr virus (EBV).
Nefiracetam
go.drugbank.com/drugs/DB13082InvestigationalNefiracetam has been used in trials studying the treatment of Alzheimer's Disease.
Categories: Compounds used in a research, industrial, or household settingMetrifonate
go.drugbank.com/drugs/DB11473ExperimentalVet approvedMetrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Categories: Compounds used in a research, industrial, or household settingEliprodil
go.drugbank.com/drugs/DB12869InvestigationalEliprodil has been used in trials studying the treatment of Parkinson Disease and Movement Disorders.
Categories: Compounds used in a research, industrial, or household settingAgkistrodon piscivorus antivenin
go.drugbank.com/drugs/DB13894ApprovedThe cottonmouth, Agkistrodon piscivorus, is a large, venomous snake in the pit viper subfamily (Crotalinae). … Approximately 99% of all venomous snake bites in the United States are caused by Crotalidae, also known as _pit vipers_.