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Displaying results 4041 - 4050 of 10000 in total
  1. Drug

    Dapoxetine

    go.drugbank.com/drugs/DB04884
    Investigational

    In October 2005, the company received a FDA Non-Approvable letter from the FDA, at which time they planned to work with regulators to address outstanding questions. … In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo.

    Mixtures: DAPOXIL 30/50 MG FILM KAPLI TABLET,18 FILM KAPLI TABLET, DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  2. Drug

    Pipenzolate

    go.drugbank.com/drugs/DB13844
    Investigational

    Mixtures: ASILON SUSPANSIYON 100 ML SUSPANSIYON, LIBKOL FILM TABLET, 50 ADETCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Tolperisone

    go.drugbank.com/drugs/DB06264
    Investigational

    It possesses a high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and peripheral nerves. … Its precise mechanism is not completely understood, though it blocks sodium and calcium channels.

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: TOLPERISON-NEURAX 50 MG, Netolp 50 mg Film Kaplı Tablet, 30 ADET
  4. Pathway

    Acylcarnitine 10-methyltridecanoylcarnitine

    smpdb.ca/view/SMP0123625
    Metabolic

    10-methyltridecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-methyltridecanoyl-CoA reacts with L-carnitine to form 10-methyltridecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  5. Pathway

    Acylcarnitine 10-Methylheptadecanoylcarnitine

    smpdb.ca/view/SMP0123667
    Metabolic

    10-Methylheptadecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-methylheptadecanoyl-CoA reacts with L-carnitine to form 10-methylheptadecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  6. Pathway

    Acylcarnitine 10-Methylhenicosanoylcarnitine

    smpdb.ca/view/SMP0123734
    Metabolic

    10-Methylhenicosanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-methylhenicosanoyl-CoA reacts with L-carnitine to form 10-methylhenicosanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  7. Pathway

    Acylcarnitine 10-Hydroxyundecanoylcarnitine

    smpdb.ca/view/SMP0123945
    Metabolic

    10-Hydroxyundecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-hydroxyundecanoyl-CoA reacts with L-carnitine to form 10-hydroxyundecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  8. Pathway

    Acylcarnitine 10-Hydroxydodecanoylcarnitine

    smpdb.ca/view/SMP0124092
    Metabolic

    10-Hydroxydodecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-hydroxydodecanoyl-CoA reacts with L-carnitine to form 10-hydroxydodecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  9. Pathway

    Acylcarnitine 10-Hydroxypentadecanoylcarnitine

    smpdb.ca/view/SMP0124222
    Metabolic

    10-Hydroxypentadecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-hydroxypentadecanoyl-CoA reacts with L-carnitine to form 10-hydroxypentadecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  10. Drug

    Nuvaxovid

    go.drugbank.com/drugs/DB15810
    ApprovedInvestigational

    Nuvaxovid (NVX-CoV2373) contains a recombinant mutant S protein that is codon-optimized for baculovirus-mediated expression in Sf9 cells derived from _Spodoptera frugiperda_ together with a Matrix-M adjuvant … [L42450,L42965] An updated formulation covering the Omicron XBB.1.5 subvariant was approved in October 2023 in the EU[L48897] and in December 2023 in Canada.

    Synonyms: SARS-CoV-2 rS, SARS-CoV-2 rS Nanoparticle VaccineCategories: COVID-19 Vaccines