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Pentaerythritol tetranitrate
go.drugbank.com/drugs/DB06154ApprovedWithdrawnInterestingly, this drug was studied for potential benefits in chronic ischemic heart failure patients. … It is a pentaerythritol nitrate in which all four hydroxy groups of pentaerythritol have been converted to the corresponding nitrate ester.
LC16M8
go.drugbank.com/drugs/DB05019InvestigationalIt is the only attenuated vaccine to be licensed for use in humans to prevent smallpox infection.
Gantenerumab
go.drugbank.com/drugs/DB12034InvestigationalAs the classical view of AD pathology posits that Aβ accumulation triggers tau hyperphosphorylation and aggregation to form NFTs and cause neurodegeneration, large efforts have gone into developing treatments … Despite the clear association of Aβ aggregation with AD, treatments aimed at preventing Aβ aggregation or removing pre-existing Aβ plaques have shown little to no clinical benefit thus far and remain controversial
Talaporfin
go.drugbank.com/drugs/DB11812InvestigationalTalaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia.
Categories: Heterocyclic Compounds with 4 or More RingsCoumaphos
go.drugbank.com/drugs/DB11390ExperimentalVet approvedIt is non-volatile in nature and is well known by a variety of names as such a _dip_ or _wash_. Coumaphos is widely used for both farm and domestic animals to control ticks, mites, flies and fleas.
Categories: Compounds used in a research, industrial, or household settingNelutroctiv
go.drugbank.com/drugs/DB21554InvestigationalNelutroctiv is under investigation in clinical trial NCT05662215 (A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants).
Actinium Ac 225 dotatate
go.drugbank.com/drugs/DB23632InvestigationalActinium Ac 225 dotatate is under investigation in clinical trial NCT07150806 (RYZ101 for the Treatment of Progressive or Recurrent Intracranial Meningioma).
KB3305
go.drugbank.com/drugs/DB06349ExperimentalKB3305 is an investigational liver selective antagonist for the glucocorticoid receptor, developed by Karo Bio for the treatment of Type 2 Diabetes.
LErafAON
go.drugbank.com/drugs/DB04973InvestigationalNeoPharm is developing liposome-encapsulated, c-Raf antisense oligodeoxynucleotides (LErafAON) for the potential treatment of various solid tumors, including those that have become resistant to radiation … or chemotherapy.