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Cannabidivarin
go.drugbank.com/drugs/DB14050InvestigationalIn October 2017 CBDV was given orphan designation by the European Medicines Agency for use in Rett Syndrome [L2952] and again in February 2018 for treatment of Fragile X Syndrome [L2951]. … They will continue to study its use in epilepsy, however, and are expanding their investigations to include its potential use in Autism Spectrum Disorder, Rett syndrome and Fragile X among others [L2949
Synonyms: 2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-propylbenzene-1,3-diolNOX-100
go.drugbank.com/drugs/DB05799InvestigationalNOX-100 is the first in a series of proprietary NO neutralizing compounds Medinox is developing to bind and inactivate NO, a simple gas molecule that is a key biological messenger in the body. … NOX-100 is the new nitric oxide (NO) neutralizing agent being developed by San Diego-based Medinox -- demonstrated its effectiveness and potential as a therapeutic to treat hemorrhagic shock.
Rifapentine
go.drugbank.com/drugs/DB01201ApprovedInvestigationalSpecifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme. … Rifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells.
Categories: Antiinfectives for Systemic Use, Drugs for Treatment of TuberculosisAeroLEF
go.drugbank.com/drugs/DB05000InvestigationalAeroLEF™ is in development for the treatment of moderate to severe pain, including cancer pain. … for patients experiencing acute pain episodes.
Leronlimab
go.drugbank.com/drugs/DB05941InvestigationalLeronlimab, or PRO-140, is a human monoclonal antibody developed by CytoDyn.[L12684] It was first described in the literature in 2001. … [A3922] This antibody binds to CCR5, which may be useful in treating HIV, cancers, and severely ill COVID-19 patients.[A192846,A192858,L12684]
Categories: Experimental Unapproved Treatments for COVID-19AGRO100
go.drugbank.com/drugs/DB04998InvestigationalAGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells. … Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell.
Synonyms: Nucleic acid aptamer binding to tumor cell nucleonFianlimab
go.drugbank.com/drugs/DB18858InvestigationalFianlimab is under investigation in clinical trial NCT06190951 (A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 or
Epinastine
go.drugbank.com/drugs/DB00751ApprovedEpinastine is used for the prevention of itching associated with allergic conjunctivitis. … It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding
Mixtures: FLURINOL(R) D COMPRIMIDOS DE LIBERACION MODIFICADATM30339
go.drugbank.com/drugs/DB05085ExperimentalTM30339 thus imitates a natural mechanism, a satiety signal from the gastrointestinal system involved in the regulation of food intake in humans. TM30339 is developed for the treatment of obesity. … TM30339 works through the same receptor as the natural satiety hormone, Pancreatic Polypeptide (PP), but TM30339 has improved properties compared with PP.
Sudapyridine
go.drugbank.com/drugs/DB18984InvestigationalSudapyridine is under investigation in clinical trial NCT05824871 (Sudapyridine (WX-081) in Rr/mdr/xdr-tuberculosis Patients).